CAS 80680-06-4

Tefludazine

Description:

Tefludazine, identified by its CAS number 80680-06-4, is a chemical compound that belongs to the class of antihistamines. It is primarily used for its antiallergic properties, functioning as a selective antagonist of the H1 histamine receptor. Tefludazine exhibits a range of pharmacological effects, including the alleviation of allergic symptoms such as rhinitis and urticaria. The compound is characterized by its ability to cross the blood-brain barrier, which may contribute to both its therapeutic effects and potential side effects, such as sedation. In terms of its chemical structure, Tefludazine features a unique arrangement of functional groups that contribute to its biological activity. It is typically administered in oral form and is subject to metabolic processes in the liver. As with many antihistamines, the safety profile of Tefludazine includes considerations for potential interactions with other medications and contraindications in certain populations. Overall, Tefludazine represents a significant option in the management of allergic conditions.

Formula: C₂₂H₂₄F₄N₂O

InChI: InChI=1/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2/t19-,21+/s2

InChI key: InChIKey=JSBWGXQXCRYYTG-LMPOMZQGNA-N

SMILES: C(F)(F)(F)C=1C=C2C([C@@H](C[C@H]2N3CCN(CCO)CC3)C4=CC=C(F)C=C4)=CC1

Synonyms:

• Lu 18-012
• Tefludazine
• rel-4-[(1R,3S)-3-(4-Fluorophenyl)-2,3-dihydro-6-(trifluoromethyl)-1H-inden-1-yl]-1-piperazineethanol
• 1-Piperazineethanol, 4-[3-(4-fluorophenyl)-2,3-dihydro-6-(trifluoromethyl)-1H-inden-1-yl]-, trans-(±)-
• 1-Piperazineethanol, 4-[(1R,3S)-3-(4-fluorophenyl)-2,3-dihydro-6-(trifluoromethyl)-1H-inden-1-yl]-, rel-

Tefludazine

CAS: 80680-06-4

Tefludazine

Purity: ≥98%

Molecular weight: 408.43g/mol

Ref: 54-BUP07330

Tefludazine

CAS: 80680-06-4

Tefludazine - a neuroleptic, benzindone derivative with oral potency, antagonizes DA and 5-HT receptors, treats psychiatric disorders.

Formula: C₂₂H₂₄F₄N₂O

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 408.43

Ref: TM-T67811