CAS 80685-23-0

2-amino-8-bromo-9-[(2-hydroxyethoxy)methyl]-3,9-dihydro-6H-purin-6-one

Description:

2-amino-8-bromo-9-[(2-hydroxyethoxy)methyl]-3,9-dihydro-6H-purin-6-one, with the CAS number 80685-23-0, is a purine derivative characterized by its complex structure that includes an amino group, a bromine atom, and a hydroxyethoxy side chain. This compound typically exhibits properties associated with purines, such as potential biological activity, particularly in the context of nucleoside analogs. The presence of the amino and hydroxyethoxy groups suggests it may engage in hydrogen bonding, influencing its solubility and reactivity. The bromine substitution can enhance its pharmacological properties, potentially affecting its interaction with biological targets. As a dihydropurine, it may exist in a tautomeric form, impacting its stability and reactivity. This compound may be of interest in medicinal chemistry, particularly in the development of antiviral or anticancer agents, due to its structural similarities to naturally occurring nucleobases. Its synthesis and characterization would typically involve standard organic chemistry techniques, and its biological activity would require further investigation through in vitro and in vivo studies.

Formula: C₈H₁₀BrN₅O₃

InChI: InChI=1/C8H10BrN5O3/c9-7-11-4-5(12-8(10)13-6(4)16)14(7)3-17-2-1-15/h15H,1-3H2,(H3,10,12,13,16)

SMILES: C(COCn1c2c(c(nc(=N)[nH]2)O)nc1Br)O

Synonyms:

• 2-amino-8-bromo-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one
• 6H-purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-

8-Hydroxyacyclovir

Controlled Product

CAS: 80685-23-0

Applications Acyclovir (A192400) is the parent compound for 8-Hydroxyacyclovir. Acyclovir (ACV), an anti-virus drug, was widely detected in natural water at concns. . ranging from ng L-1 to μg L-1 due to inefficient biol. treatments in sewage treatment plant.
References Zhang, Q., et al.: Journal of Radioanalytical and Nuclear Chemistry, 320, 823 (2019);

Formula: C₈H₁₁N₅O₄

Color and Shape: Neat

Molecular weight: 241.204

Ref: TR-H806850

8-Hydroxyacyclovir

CAS: 80685-23-0

8-Hydroxyacyclovir is an analog of acyclovir, a drug used to treat viral infections. It is a potent inhibitor of protein kinase and has been shown to induce apoptosis in cancer cells. This compound has anti-tumor activity and shows promise as an anticancer agent. In Chinese medicine, indirubin, which is structurally similar to 8-hydroxyacyclovir, has been used as an anticancer agent for centuries. 8-Hydroxyacyclovir inhibits the activity of kinases involved in cell division and growth, leading to the death of cancer cells. It has been detected in human urine after administration, making it a potential candidate for use as a therapeutic agent for cancer treatment.

Formula: C₈H₁₁N₅O₄

Purity: Min. 95%

Molecular weight: 241.2 g/mol

Ref: 3D-FDA68523

8-Hydroxy Acyclovir

CAS: 80685-23-0

Formula: C₈H₁₁N₅O₄

Molecular weight: 241.21

Ref: ST-EA-CP-A8025