CAS 807-38-5

Fluocinolone

Description:

Fluocinolone, with the CAS number 807-38-5, is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties. It is characterized by its ability to inhibit the release of inflammatory mediators, making it effective in treating various skin conditions, such as eczema and psoriasis. Fluocinolone is typically available in topical formulations, including creams, ointments, and solutions, allowing for localized treatment with minimal systemic absorption. The compound exhibits a high affinity for glucocorticoid receptors, which contributes to its potency and efficacy. Its chemical structure includes a fluorinated steroid backbone, which enhances its stability and activity compared to non-fluorinated corticosteroids. Fluocinolone is generally well-tolerated, but prolonged use can lead to side effects such as skin thinning or systemic absorption issues. As with all corticosteroids, it is essential to use fluocinolone under medical supervision to mitigate potential adverse effects and ensure appropriate therapeutic outcomes.

Formula: C₂₁H₂₆F₂O₆

InChI: InChI=1S/C21H26F2O6/c1-18-4-3-10(25)5-13(18)14(22)6-12-11-7-15(26)21(29,17(28)9-24)19(11,2)8-16(27)20(12,18)23/h3-5,11-12,14-16,24,26-27,29H,6-9H2,1-2H3/t11-,12-,14-,15+,16-,18-,19-,20-,21-/m0/s1

InChI key: InChIKey=UUOUOERPONYGOS-CLCRDYEYSA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](O)C3)[H])(C[C@H](F)C=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• (6Alpha,11Beta,16Alpha)-6,9-Difluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
• (6α,11β,16α)-6,9-Difluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
• 16α-Hydroxy-6α,9-difluoroprednisolone
• 6α-Fluorotriamcinolone
• Fluocinolone
• Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,16,17,21-tetrahydroxy-, (6α,11β,16α)-
• Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,16α,17,21-tetrahydroxy-

Fluocinolone Acetonide EP Impurity C

CAS: 807-38-5

Formula: C₂₁H₂₆F₂O₆

Molecular weight: 412.43

Ref: ST-EA-CP-F56003

(6α,11β,16α)-6,9-Difluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione

CAS: 807-38-5

Formula: C₂₁H₂₆F₂O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 412.4243

Ref: IN-DA00G4SA

Fluocinolone

CAS: 807-38-5

Fluocinolone

Purity: 97%

Molecular weight: 412.42g/mol

Ref: 54-PC110461

Fluocinolone Acetonide EP Impurity C (Fluocinolone)

CAS: 807-38-5

Formula: C₂₁H₂₆F₂O₆

Color and Shape: White To Off-White Solid

Molecular weight: 412.43

Ref: 4Z-F-118003

Fluocinolone

CAS: 807-38-5

Molecular weight: 412.43

Ref: 10-F986281

Fluocinolone

Controlled Product

CAS: 807-38-5

Impurity Fluocinolone Acetonide EP Impurity C
Applications Fluocinolone, is a medication, used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin condition. It is also a derivative of Fluocinolone Acetonide (F455800).
References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),

Formula: C₂₁H₂₆F₂O₆

Color and Shape: Neat

Molecular weight: 412.42

Ref: TR-F455795

6-alpha,9-alpha-Difluoro-11-beta,16-alpha,17-alpha,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione

Controlled Product

CAS: 807-38-5

Fluocinolone acetonide is a corticosteroid with anti-inflammatory, immunosuppressive, and anti-allergic effects. It is used to treat eye disorders such as uveitis and chronic iritis. The mechanism of action of fluocinolone acetonide is not completely understood. Fluocinolone acetonide has been shown to have a short-term effect on reducing inflammation in the eye, but its efficacy for long-term use is questionable. Low doses of fluocinolone acetonide may be less potent than higher doses because they do not bind well to the receptor sites in the retina. This means that low-dose fluocinolone acetonide may not have an adequate therapeutic effect on uveitis or other eye disorders.

Formula: C₂₁H₂₆F₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 412.42 g/mol

Ref: 3D-FD101918