CAS 80751-65-1

SKF 82958

Description:

SKF 82958, with the CAS number 80751-65-1, is a chemical compound that belongs to the class of selective dopamine D1 receptor agonists. It is primarily studied for its potential therapeutic applications in neurological disorders, particularly in the context of Parkinson's disease and other conditions associated with dopaminergic dysfunction. The compound exhibits a high affinity for dopamine D1 receptors, which are involved in various physiological processes, including motor control and cognitive functions. SKF 82958 is known to enhance dopaminergic signaling, which may lead to improved motor function in animal models. Its pharmacological profile suggests that it could have both stimulant and neuroprotective effects. However, like many compounds that interact with the central nervous system, it may also present side effects or risks, necessitating careful evaluation in clinical settings. Research on SKF 82958 continues to explore its mechanisms of action, efficacy, and safety in various therapeutic contexts.

Formula: C₁₉H₂₀ClNO₂

InChI: InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2

InChI key: InChIKey=HJWHHQIVUHOBQN-UHFFFAOYSA-N

SMILES: ClC1=C2C(C(CN(CC=C)CC2)C3=CC=CC=C3)=CC(O)=C1O

Synonyms:

• (+/-)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
• (±)-Skf 82958
• 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-
• 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-
• 1H-3-benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-, hydrobromide (1:1)
• 3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide (1:1)
• 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-1H-3-benzazepine-7,8-diol
• 3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol

1H-3-Benzazepine-7,8-diol,6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propen-1-yl)-

CAS: 80751-65-1

Formula: C₁₉H₂₀ClNO₂

Purity: 98%

Molecular weight: 329.8206

Ref: IN-DA008LYY

Chloro-APB hydrobromide

CAS: 80751-65-1

Formula: C₁₉H₂₀ClNO₂·HBr

Molecular weight: 410.73

Ref: 7W-GL3365

Chloro-apb hydrobromide

CAS: 80751-65-1

Chloro-apb hydrobromide is a drug that has been shown to have both inhibitory and stimulatory effects on dopamine receptors. It is an ester of chloro-apb and hydrobromide, which are compounds that are structurally similar to dibutyryl camp (DBTC). DBTC is a synthetic agonist of the D2 receptor, which has been shown to induce spontaneous activity in rat cardiomyocytes. Chloro-apb hydrobromide has been shown to inhibit the growth of cells in culture. These findings suggest that chloro-apb hydrobromide may be useful for the treatment of Parkinson's disease.

Formula: C₁₉H₂₁BrClNO₂

Purity: Min. 95%

Molecular weight: 410.7 g/mol

Ref: 3D-FDA75165

SKF-82958

CAS: 80751-65-1

SKF 82958 is a D1/D5 receptor full agonist.

Formula: C₁₉H₂₀ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 329.82

Ref: TM-T16893