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CAS 80755-51-7

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Bunazosin

Description:
Bunazosin is a pharmaceutical compound primarily classified as an alpha-1 adrenergic antagonist, which is used mainly in the treatment of hypertension and benign prostatic hyperplasia. Its mechanism of action involves blocking alpha-1 adrenergic receptors, leading to vasodilation and a subsequent decrease in blood pressure. The chemical structure of Bunazosin includes a piperazine ring, which contributes to its pharmacological properties. It is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing in clinical settings. Bunazosin is characterized by its moderate solubility in water and its ability to cross biological membranes, which is essential for its therapeutic effects. As with many medications, potential side effects may include dizziness, fatigue, and orthostatic hypotension. Due to its specific action on adrenergic receptors, Bunazosin is often considered in the context of other antihypertensive agents, providing an alternative for patients who may not respond well to standard treatments.
Formula:C19H27N5O3
InChI:InChI=1S/C19H27N5O3/c1-4-6-17(25)23-7-5-8-24(10-9-23)19-21-14-12-16(27-3)15(26-2)11-13(14)18(20)22-19/h11-12H,4-10H2,1-3H3,(H2,20,21,22)
InChI key:InChIKey=RHLJLALHBZGAFM-UHFFFAOYSA-N
SMILES:NC=1C2=C(N=C(N1)N3CCN(C(CCC)=O)CCC3)C=C(OC)C(OC)=C2
Synonyms:
  • 1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)hexahydro-1H-1,4-diazepin-1-yl]-1-butanone
  • 1H-1,4-Diazepine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)hexahydro-4-(1-oxobutyl)-
  • 1-Butanone, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)hexahydro-1H-1,4-diazepin-1-yl]-
  • E 1015
  • Bunazosin
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Found 3 products.