CymitQuimica logo

CAS 80791-93-1

:

2''-DEOXY-2''-FLUORO-5-IODOCYTIDINE

Description:
2'-Deoxy-2'-fluoro-5-iodocytidine, commonly referred to as F-ara-C, is a nucleoside analog that incorporates a fluorine atom at the 2' position and an iodine atom at the 5' position of the cytidine structure. This modification enhances its stability and bioactivity compared to natural nucleosides. The presence of the fluorine atom contributes to its resistance to enzymatic degradation, making it a valuable compound in antiviral and anticancer research. F-ara-C is primarily studied for its potential therapeutic applications, particularly in the treatment of viral infections and certain types of cancer, as it can interfere with nucleic acid synthesis. The compound exhibits a unique mechanism of action, often leading to the inhibition of DNA polymerase, which is crucial for DNA replication. Its chemical structure allows for incorporation into DNA, resulting in cytotoxic effects in rapidly dividing cells. As with many nucleoside analogs, the pharmacokinetics and biological activity of 2'-deoxy-2'-fluoro-5-iodocytidine are subjects of ongoing research to optimize its therapeutic efficacy and minimize potential side effects.
Formula:C9H11FIN3O4
Synonyms:
  • 2''-DEOXY-2''-FLUORO-5-IODOCYTIDINE
  • 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin-2-one
  • 4-AMINO-1-((3R,4R,5R)-3-FLUORO-4-HYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-5-IODOPYRIMIDIN-2(1H)-ONE
  • 5-Iodo-2'-fluoro-2'-deoxycytidine
  • Cytidine, 2'-deoxy-2'-fluoro-5-iodo-
  • 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one
  • 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 1 products.