CAS 808-48-0

Desoxycorticosterone pivalate

Description:

Desoxycorticosterone pivalate, with the CAS number 808-48-0, is a synthetic steroid hormone derived from desoxycorticosterone, which is a precursor in the biosynthesis of corticosteroids. This compound is characterized by its pivalate ester, which enhances its lipid solubility and alters its pharmacokinetic properties, allowing for prolonged action in the body. Desoxycorticosterone pivalate primarily exhibits mineralocorticoid activity, influencing electrolyte and water balance by promoting sodium retention and potassium excretion in the kidneys. It is often utilized in clinical settings for its therapeutic effects in conditions such as adrenal insufficiency and certain types of hypotension. The substance is typically administered via intramuscular injection, and its effects can be monitored through changes in blood pressure and electrolyte levels. As with other corticosteroids, potential side effects may include fluid retention, hypertension, and electrolyte imbalances. Proper medical supervision is essential when using this compound to mitigate risks and ensure effective treatment outcomes.

Formula: C₂₆H₃₈O₄

InChI: InChI=1S/C26H38O4/c1-24(2,3)23(29)30-15-22(28)21-9-8-19-18-7-6-16-14-17(27)10-12-25(16,4)20(18)11-13-26(19,21)5/h14,18-21H,6-13,15H2,1-5H3/t18-,19-,20-,21+,25-,26-/m0/s1

InChI key: InChIKey=VVOIQBFMTVCINR-WWMZEODYSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)(CC1)[H])[H])(CC[C@@H]2C(COC(C(C)(C)C)=O)=O)[H]

Synonyms:

• 11-Deoxycorticosterone, pivalate
• 21-(2,2-Dimethyl-1-oxopropoxy)pregn-4-ene-3,20-dione
• 21-Hydroxypregn-4-ene-3,20-dione pivalate
• 3,20-Dioxopregn-4-En-21-Yl 2,2-Dimethylpropanoate
• Cortexone M
• Corticosterone, deoxy-, pivalate
• Deoxycorticosterone pivalate
• Deoxycorticosterone trimethylacetate
• Deoxycortone pivalate
• Deoxycortone trimethylacetate
• Desoxycorticosterone pivalate
• Desoxycorticosterone trimethylacetate
• Desoxycortisone pivalate
• Desoxycortonpivalat
• Docp
• Dtma
• Neodin-Depositum
• Nsc 95278
• Percorten M
• Percorten Pivalate
• Pivalate De Desoxycortone
• Pivalato De Desoxicortona
• Pivalic acid, ester with 11-deoxycorticosterone
• Pregn-4-ene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-

Desoxycorticosterone Pivalate

CAS: 808-48-0

Adrenal cortical hormones and their derivatives nesoi

Formula: C₂₆H₃₈O₄

Color and Shape: White Off-White Powder

Molecular weight: 414.27701

Ref: 45-1175004

Desoxycorticosterone pivalate

CAS: 808-48-0

Formula: C₂₆H₃₈O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 414.5775

Ref: IN-DA00G2AB

Desoxycorticosterone pivalate

CAS: 808-48-0

DOCP, a mineralocorticoid, treats dogs with adrenal insufficiency.

Formula: C₂₆H₃₈O₄

Color and Shape: Solid

Molecular weight: 414.58

Ref: TM-TC0008

Desoxycorticosterone Pivalate

CAS: 808-48-0

Formula: C₂₆H₃₈O₄

Molecular weight: 414.59

Ref: 4Z-C-10422

11-Deoxy Corticosterone Pivalate

Controlled Product

CAS: 808-48-0

Applications 11-Deoxycorticosterone Pivalate is a mineralocorticoid hormone and an analog of desoxycorticosterone. 11-Deoxycorticosterone Pivalate is used in the treatment of adrenocortical insufficiency. It is used to treat in patients suffering from rheumatoid arthritis.
References Kaladhar, D.S.V.G.K. et al.: Int. J. Pham. Bio Sci., 1, 132 (2010); FDA: Fed. Reg., 63, 13121 (1998);

Formula: C₂₆H₃₈O₄

Color and Shape: White To Off-White

Molecular weight: 414.58

Ref: TR-D232580

Desoxycorticosterone pivalate

Controlled Product

CAS: 808-48-0

Desoxycorticosterone pivalate is a synthetic hormone that is used as a replacement for cortisol in the treatment of Addison's disease. It is a prodrug that is hydrolyzed to its active form, cortisone, in the liver. Desoxycorticosterone pivalate has been shown to be effective in preventing and treating chronic oral toxicity and hiv infection. This drug can also increase the permeability of water in tissues and cells by causing cell lysis, which may lead to an increased production of histamine and prostaglandins. Desoxycorticosterone pivalate has been shown to have anti-inflammatory effects on the cardiovascular system by regulating the production of cholesterol, fatty acids, and other lipids. This drug also has physiological functions such as maintaining electrolyte balance in the body and regulating blood pressure levels.

Formula: C₂₆H₃₈O₄

Purity: Min. 95%

Molecular weight: 414.58 g/mol

Ref: 3D-AAA80848