CAS 808-71-9

Penethamate hydriodide

Description:

Penethamate hydriodide is a chemical compound primarily used as an antihistamine and antiallergic agent. It is classified as a quaternary ammonium compound and is known for its ability to inhibit the action of histamine, thereby alleviating allergic symptoms. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its use in various pharmaceutical formulations. Penethamate hydriodide is often administered in the form of oral tablets or solutions. Its mechanism of action involves blocking H1 receptors, which are responsible for mediating allergic responses. Additionally, it may exhibit mild sedative effects, making it useful in treating conditions such as allergic rhinitis and urticaria. Safety and efficacy profiles are well-documented, but like all medications, it may have side effects, including drowsiness or dry mouth. Proper dosage and administration guidelines should be followed to minimize adverse effects and ensure therapeutic effectiveness.

Formula: C₂₂H₃₁N₃O₄S·HI

InChI: InChI=1S/C22H31N3O4S.HI/c1-5-24(6-2)12-13-29-21(28)18-22(3,4)30-20-17(19(27)25(18)20)23-16(26)14-15-10-8-7-9-11-15;/h7-11,17-18,20H,5-6,12-14H2,1-4H3,(H,23,26);1H/t17-,18+,20-;/m1./s1

InChI key: InChIKey=XWRCFDRXQPRCCO-FLQNVMKHSA-N

SMILES: C(OCCN(CC)CC)(=O)[C@@H]1N2[C@@]([C@H](NC(CC3=CC=CC=C3)=O)C2=O)(SC1(C)C)[H].I

Synonyms:

• 2-(diethylamino)ethyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydroiodide (1:1)
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-, 2-(diethylamino)ethyl ester, monohydriodide
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- (2S,5R,6R)-, 2-(diethylamino)ethyl ester, monohydriodide
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]- [2S-(2α,5α,6β)]-, 2-(diethylamino)ethyl ester, monohydriodide
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, 2-(diethylamino)ethyl ester, hydriodide (1:1), (2S,5R,6R)-
• Alivin
• Benzylpenicillin β-diethylaminoethyl ester hydriodide
• Bronchocillin
• Bronchopen
• Broncopen
• Deripen
• Diethylaminoethyl ester penicillin hydriodide
• Eficillin
• Ephicillin hydriodide
• Estopen
• Leocillin
• Mamyzin
• Neo-Penil
• Penethacillin
• Penethamate Hydriodide
• Penethecillin
• Penicillin G diethylaminoethyl ester hydriodide
• Penicillin G, 2-(diethylamino)ethyl ester, hydriodide
• Penicillin, 2-(diethylamino)ethyl ester, hydriodide
• Pulmaxil N
• Pulmo 500

Penethacillin Hydroiodide (Penethamate Hydroiodide)

CAS: 808-71-9

Formula: C₂₂H₃₁N₃O₄SHI

Color and Shape: White To Off-White Solid

Molecular weight: 433.57 127.91

Ref: 4Z-P-182001

Benzylpenicillin Diethylaminoethyl Ester Hydroiodide

Controlled Product

CAS: 808-71-9

Applications Benzylpenicillin Diethylaminoethyl Ester Hydroiodide is a prodrug of Benzylpenicillin. It is an antimicrobial/antibacterial agent that is used primarily in the treatment of bovine mastitis.
References Sandgren, C. et al.: Veterin. J., 175, 108 (2008); McDougall, S. et al.: J. Dairy, Sci., 92, 4421 (2009);

Formula: C₂₂H₃₂IN₃O₄S

Color and Shape: Neat

Molecular weight: 561.48

Ref: TR-B288590

Penethamate hydriodide

CAS: 808-71-9

Penethamate hydriodide is a diethylaminoethyl ester prodrug of penicillin, utilized via intramuscular injection to treat mastitis in cattle.

Formula: C₂₂H₃₂IN₃O₄S

Color and Shape: Solid

Molecular weight: 561.477

Ref: TM-T206114

Benzylpenicillin diethylaminoethyl ester hydroiodide

CAS: 808-71-9

Benzylpenicillin diethylaminoethyl ester hydroiodide is a potent broad-spectrum antimicrobial agent that inhibits the growth of bacteria by inhibiting protein synthesis. It is used to treat microbial infections and has been shown to be effective against Streptococcus species, including Streptococcus pneumoniae, Streptococcus pyogenes, and Streptococcus viridans. Benzylpenicillin diethylaminoethyl ester hydroiodide binds to the 50S ribosome subunit of bacteria and prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis. This binding prevents protein synthesis and cell division.

Formula: C₂₂H₃₂IN₃O₄S

Purity: Min. 95%

Molecular weight: 561.5 g/mol

Ref: 3D-AAA80871