CAS 80830-42-8

Fentiapril

Description:

Fentiapril, with the CAS number 80830-42-8, is a chemical compound classified as an antihypertensive agent, specifically an angiotensin-converting enzyme (ACE) inhibitor. It is primarily used in the treatment of hypertension and certain types of heart failure. The compound works by inhibiting the activity of the ACE enzyme, which plays a crucial role in the renin-angiotensin-aldosterone system (RAAS) that regulates blood pressure. By blocking this enzyme, Fentiapril helps to relax blood vessels, thereby lowering blood pressure and reducing the workload on the heart. In terms of its physical properties, Fentiapril is typically a white to off-white crystalline powder, and it is soluble in organic solvents but has limited solubility in water. As with many pharmaceuticals, it may have side effects, including dizziness, fatigue, or gastrointestinal disturbances, and its use should be monitored by healthcare professionals. Overall, Fentiapril represents a significant therapeutic option in managing cardiovascular conditions.

Formula: C₁₃H₁₅NO₄S₂

InChI: InChI=1/C13H15NO4S2/c15-10-4-2-1-3-8(10)12-14(11(16)5-6-19)9(7-20-12)13(17)18/h1-4,9,12,15,19H,5-7H2,(H,17,18)/t9-,12+/m0/s1

InChI key: InChIKey=BSHDUMDXSRLRBI-JOYOIKCWSA-N

SMILES: C(CCS)(=O)N1[C@H](SC[C@H]1C(O)=O)C2=C(O)C=CC=C2

Synonyms:

• (2R,4R)-2-(2-Hydroxyphenyl)-3-(3-mercapto-1-oxopropyl)-4-thiazolidinecarboxylic acid
• (2R,4R)-2-(2-hydroxyphenyl)-3-(3-sulfanylpropanoyl)-1,3-thiazolidine-4-carboxylic acid
• (2R,4R)-2-(o-Hydroxyphenyl)-3-(3-mercaptopropionyl)-4-thiazolidinecarboxylic acid
• 4-Thiazolidinecarboxylic acid, 2-(2-hydroxyphenyl)-3-(3-mercapto-1-oxopropyl)-, (2R,4R)-
• 4-Thiazolidinecarboxylic acid, 2-(2-hydroxyphenyl)-3-(3-mercapto-1-oxopropyl)-, (2R-cis)-
• Brn 5762860
• Ccris 2341
• Fentiapril
• Prescrin
• Rentiapril [INN]
• Rentiaprilum
• Rentiaprilum [Latin]
• Sa 446
• Sa 466
• Unii-D0Tam1017B
• Rentiapril
• (2R)-2α-(2-Hydroxyphenyl)-3-(3-mercapto-1-oxopropyl)thiazolidine-4α-carboxylic acid

Rentiapril

CAS: 80830-42-8

Rentiapril is a pharmaceutical drug that belongs to the group of angiotensin-converting enzyme (ACE) inhibitors. It is used to treat high blood pressure, heart failure, and other cardiovascular disorders. Rentiapril may also be used to treat inflammatory bowel disease (IBD), such as ulcerative colitis and Crohn's disease. Side effects of this drug include dizziness, headache, nausea, diarrhea, and chest pain.

Formula: C₁₃H₁₅NO₄S₂

Purity: Min. 95%

Molecular weight: 313.4 g/mol

Ref: 3D-FDA83042

Rentiapril

CAS: 80830-42-8

Rentiapril is an orally active inhibitor of angiotensin converting enzyme (ACE), with antihypertensive activity.

Formula: C₁₃H₁₅NO₄S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 313.39

Ref: TM-T12704