CAS 80841-78-7

4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one

Description:

4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one, with the CAS number 80841-78-7, is a chemical compound characterized by its dioxolane structure, which features a five-membered ring containing two oxygen atoms and a carbonyl group. This compound typically exhibits properties associated with both chlorinated and dioxolane derivatives, such as moderate to high reactivity due to the presence of the chloromethyl group, which can participate in nucleophilic substitution reactions. The methyl group contributes to its hydrophobic character, influencing its solubility in organic solvents. The dioxolane ring can also impart stability to the molecule, making it useful in various synthetic applications, particularly in organic synthesis and medicinal chemistry. Additionally, the compound may exhibit biological activity, although specific biological properties would depend on the context of its use and the presence of functional groups. Safety data should be consulted for handling and storage, as chlorinated compounds can pose health risks.

Formula: C₅H₅ClO₃

InChI: InChI=1S/C5H5ClO3/c1-3-4(2-6)9-5(7)8-3/h2H2,1H3

InChI key: InChIKey=QCLFSYYUWPUWQR-UHFFFAOYSA-N

SMILES: C(Cl)C1=C(C)OC(=O)O1

Synonyms:

• (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl chloride
• 1,3-Dioxol-2-one, 4-(chloromethyl)-5-methyl-
• 4-(Chloromethyl)-5-Methyl-1,3-Dioxol-2-Ketone
• 4-(Chloromethyl)-5-methyldioxol-2-one
• 4-(Cyclomethyl carbonyl)-5-methyl-1,3-dioxol-2-one
• 4-Chloromethyl-5-Methyl-1,3-Dioxolene-2-One
• 4-Chloromethyl-5-methyl-2-oxo-1,3-dioxole
• 4-Cloromethyl-5-Methyl-1,3-Dioxol-2-One
• Dmdo-Cl
• Olm 45
• 4-chloromethyl-5-methyl-1,3-dioxol-2-one
• 4-Chloro Methyl-5-Methyl-1,3-Dioxolene-2-One

4-Chloromethyl-5-methyl-2-oxo-1,3-dioxole, 97%

CAS: 80841-78-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₅H₅ClO₃

Purity: 97%

Molecular weight: 148.54

Ref: 02-H55735

4-Chloromethyl-5-methyl-1,3-dioxol-2-one

CAS: 80841-78-7

Formula: C₅H₅ClO₃

Purity: 97%

Color and Shape: Liquid

Molecular weight: 148.5444

Ref: IN-DA003405

Olmesartan Medoxomil Impurity 5

CAS: 80841-78-7

Formula: C₅H₅ClO₃

Color and Shape: Pale Yellow Liquid

Molecular weight: 148.54

Ref: 4Z-O-0823

4-Chloromethyl-5-methyl-1,3-dioxol-2-one

CAS: 80841-78-7

4-Chloromethyl-5-methyl-1,3-dioxol-2-one

Formula: C₅H₅ClO₃

Purity: 95%

Color and Shape: dark brown liquid

Molecular weight: 148.54g/mol

Ref: 54-OR53058

4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one

CAS: 80841-78-7

Color and Shape: Neat

Ref: 86-MM1317.18

4-Chloromethyl-5-methyl-1,3-dioxol-2-one

CAS: 80841-78-7

Formula: C₅H₅ClO₃

Purity: >94.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 148.54

Ref: 3B-C1882

4-Chloromethyl-5-methyl-1,3-dioxol-2-one

Controlled Product

CAS: 80841-78-7

Applications 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is also used in the preparation of prodrugs of ampicillin.
References Ikeda, S. et al.: Chem. Pharmac. Bull., 32, 4316 (1984); Wu, T. Yaox. Xueb., 41, 537 (2006);

Formula: C₅H₅ClO₃

Color and Shape: Neat

Molecular weight: 148.54

Ref: TR-C369335

Olmesartan Medoxomil Impurity 5

CAS: 80841-78-7

Formula: C₅H₅ClO₃

Molecular weight: 148.54

Ref: ST-EA-CP-O7007

4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one

CAS: 80841-78-7

Formula: C₅H₅ClO₃

Purity: 95%

Color and Shape: Liquid, Clear

Molecular weight: 148.54

Ref: 10-F079667