CAS 808756-71-0

ABT 102

Description:

ABT-102, with the CAS number 808756-71-0, is a chemical compound that belongs to the class of compounds known as selective serotonin reuptake inhibitors (SSRIs). It is primarily investigated for its potential therapeutic effects in treating mood disorders, particularly depression and anxiety. The compound exhibits a high affinity for serotonin receptors, which plays a crucial role in modulating mood and emotional responses. ABT-102 is characterized by its ability to enhance serotonin levels in the synaptic cleft by inhibiting its reuptake into presynaptic neurons, thereby increasing serotonin availability for receptor binding. Additionally, it may possess neuroprotective properties, contributing to its potential efficacy in neuropsychiatric conditions. The compound's pharmacokinetics, including absorption, distribution, metabolism, and excretion, are essential for understanding its therapeutic profile and safety. Ongoing research aims to elucidate its full range of biological effects and potential applications in clinical settings.

Formula: C₂₁H₂₄N₄O

InChI: InChI=1S/C21H24N4O/c1-21(2,3)14-8-9-15-13(11-14)7-10-18(15)24-20(26)23-17-5-4-6-19-16(17)12-22-25-19/h4-6,8-9,11-12,18H,7,10H2,1-3H3,(H,22,25)(H2,23,24,26)/t18-/m1/s1

InChI key: InChIKey=TYOYXJNGINZFET-GOSISDBHSA-N

SMILES: N(C(NC1=C2C(NN=C2)=CC=C1)=O)[C@H]3C=4C(=CC(C(C)(C)C)=CC4)CC3

Synonyms:

• ABT 102
• 1-[(1R)-5-tert-Butyl-2,3-dihydro-1H-inden-1-yl]-3-(1H-indazol-4-yl)urea
• N-(5-tert-Butylindan-4-yl)-N′-(1H-indazol-4-yl)-urea
• N-[(1R)-5-(1,1-Dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N′-1H-indazol-4-ylurea
• Urea, N-[(1R)-5-(1,1-dimethylethyl)-2,3-dihydro-1H-inden-1-yl]-N′-1H-indazol-4-yl-

ABT 102

CAS: 808756-71-0

ABT 102

Purity: ≥98%

Molecular weight: 348.44g/mol

Ref: 54-BUP12433

ABT 102

CAS: 808756-71-0

ABT 102 is a water-soluble drug that belongs to the class of compounds. It has a particle size of less than 10 microns and is soluble in water. ABT 102 is able to bind to benzyl groups and form solid dispersions. This drug potently inhibits receptor activity in vitro, as shown by its ability to inhibit the binding of ligands to their corresponding receptors in a dose-dependent manner. In vivo experiments have shown that ABT 102 has potential clinical efficacy against bone cancer. The linear regression analysis of data from human trials shows that there is a statistically significant correlation between plasma concentration and receptor occupancy for ABT 102. Hydrogen bond interactions with cation channels may be responsible for the observed increase in plasma concentration following oral administration.

Formula: C₂₁H₂₄N₄O

Purity: Min. 95%

Molecular weight: 348.4 g/mol

Ref: 3D-IHB75671

ABT 102

CAS: 808756-71-0

ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.

Formula: C₂₁H₂₄N₄O

Purity: 98.38% - 99.86%

Color and Shape: Solid

Molecular weight: 348.44

Ref: TM-T29522