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CAS 80902-29-0

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  • Rp-dGTPαS
    Targetmol
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    Rp-dGTPαS

    CAS:
    Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates [1].
    Formula:C10H16N5O12P3S
    Color and Shape:Solid
    Molecular weight:523.25

    Ref: TM-T84664