CAS 80927-55-5

2(1H)-Pyrimidinone,6-chloro-

Description:

2(1H)-Pyrimidinone, 6-chloro- is a heterocyclic organic compound characterized by a pyrimidine ring structure that includes a carbonyl group (ketone) and a chlorine substituent at the 6-position. This compound typically exhibits properties associated with pyrimidinones, such as being a solid at room temperature and having moderate solubility in polar solvents due to the presence of the carbonyl group. The chlorine atom introduces additional reactivity, making it a potential candidate for various chemical reactions, including nucleophilic substitutions. Its structure allows for potential applications in pharmaceuticals and agrochemicals, as pyrimidine derivatives are often explored for their biological activities. The compound's molecular interactions can be influenced by the electron-withdrawing nature of the chlorine atom, which may affect its acidity and reactivity. Overall, 2(1H)-Pyrimidinone, 6-chloro- is a versatile compound with significant implications in synthetic chemistry and medicinal research.

Formula: C₄H₃ClN₂O

Synonyms:

• 2(1H)-Pyrimidinone,4-chloro- (6CI,9CI)
• 2-Pyrimidinol,4-chloro-
• 6-chloro-1H-pyrimidin-2-one
• Benzoicacid,5-(chlorosulfonyl)-,methylester
• 4-chloropyrimidin-2(1H)-one
• Pazopanib Related Compound 1
• Pazopanib Impurity 12
• 6-Chloropyrimidin-2(1H)-one
• 4-chloropyrimidin-2(1H)-one80927-55-5
• 4-Chloro-2-hydroxypyrimidine
• 2(1H)-Pyrimidinone,6-chloro-

2(1H)-Pyrimidinone, 4-chloro- (6CI,9CI)

CAS: 80927-55-5

Formula: C₄H₃ClN₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 130.5324

Ref: IN-DA00G7Z7

6-Chloropyrimidin-2(1H)-one·xhydrate

CAS: 80927-55-5

6-Chloropyrimidin-2(1H)-one·xhydrate

Purity: 95% （xhydrate）

Molecular weight: 130.53g/mol

Ref: 54-OR1074734

Pazopanib Impurity 57

CAS: 80927-55-5

Formula: C₄H₃ClN₂O

Molecular weight: 130.53

Ref: 4Z-P-129003

6-Chloropyrimidin-2(1H)-one

CAS: 80927-55-5

Formula: C₄H₃ClN₂O

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 130.53

Ref: 10-F238722

6-Chloropyrimidin-2(1H)-one

CAS: 80927-55-5

6-Chloropyrimidin-2(1H)-one is a naphthalene derivative that is used as an antimicrobial agent. It inhibits the growth of bacteria and cancer cells by inhibiting the synthesis of DNA, RNA, and proteins. 6-Chloropyrimidin-2(1H)-one blocks the production of lp-pla2 protein by binding to the hydroxyl group on the C4 carbon atom, which prevents it from being converted into a reactive form. This compound also inhibits the development of inflammatory bowel disease by blocking piperazine synthesis. 6-Chloropyrimidin-2(1H)-one has been shown to inhibit the colonic inflammation induced by ischemia reperfusion in rats. This may be due to its ability to inhibit nitrogen atoms in bowel disease.

Formula: C₄H₃ClN₂O

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 130.53 g/mol

Ref: 3D-FDA92755

6-Chloropyrimidin-2(1H)-one

CAS: 80927-55-5

Formula: C₄H₃ClN₂O

Molecular weight: 130.53

Ref: ST-EA-CP-P58004