CAS 80937-34-4
:gilvocarcin E
Description:
Gilvocarcin E is a naturally occurring antibiotic compound that belongs to the class of anthracycline antibiotics. It is derived from the fermentation of certain strains of the bacterium Micromonospora. This compound exhibits notable antitumor activity, primarily by intercalating into DNA and inhibiting topoisomerase II, which disrupts DNA replication and transcription processes in cancer cells. Gilvocarcin E is characterized by its complex molecular structure, which includes multiple aromatic rings and functional groups that contribute to its biological activity. The compound is typically studied for its potential therapeutic applications in oncology, particularly against various types of cancer. Additionally, its unique mechanism of action and structural features make it a subject of interest in medicinal chemistry and drug development. However, like many antibiotics, its use may be limited by factors such as toxicity and resistance, necessitating further research to optimize its therapeutic potential while minimizing adverse effects.
Formula:C27H28O9
InChI:InChI=1/C27H28O9/c1-5-12-8-15-19(17(9-12)33-3)14-10-18(34-4)21-16(29)7-6-13(20(21)25(14)36-27(15)32)26-23(31)22(30)24(35-26)11(2)28/h6-11,22-24,26,28-31H,5H2,1-4H3/t11-,22-,23-,24+,26-/m1/s1
Synonyms:- 6H-Benzo[d]naphtho[1,2-b]pyran-6-one, 4-(6-deoxy-α-D-galactofuranosyl)-8-ethyl-1-hydroxy-10,12-dimethoxy-
- Anandimycin C
- 8-Ethyl-4-(6-deoxy-α-L-galactofuranosyl)-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one
- Toromycin C
- gilvocarcin E
- 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 4-(6-deoxy-alpha-galactofuranosyl)-8-ethyl-1-hydroxy-10,12-dimethoxy-
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Gilvocarcin E
CAS:<p>Gilvocarcin E exhibits activity against Gram-positive bacteria and is capable of inhibiting Sarcoma 180 and P388 leukemia cells.</p>Formula:C27H28O9Color and Shape:SolidMolecular weight:496.506
