CAS 81-55-0

1,8-Dihydroxy-4,5-dinitro-9,10-anthracenedione

Description:

1,8-Dihydroxy-4,5-dinitro-9,10-anthracenedione, commonly referred to as "DHA," is an organic compound belonging to the anthraquinone family. It is characterized by its distinct structure, which includes two hydroxyl groups and two nitro groups attached to the anthracene backbone. This compound typically appears as a dark-colored solid and is known for its potential applications in dyeing and as a pigment due to its strong chromophoric properties. The presence of the nitro groups contributes to its reactivity and can influence its electronic properties, making it useful in various chemical reactions. Additionally, the hydroxyl groups can participate in hydrogen bonding, affecting its solubility and interaction with other substances. Due to its chemical structure, 1,8-Dihydroxy-4,5-dinitro-9,10-anthracenedione may exhibit biological activity, which has been the subject of research in fields such as medicinal chemistry and environmental science. However, handling this compound requires caution due to its potential toxicity and environmental impact.

Formula: C₁₄H₆N₂O₈

InChI: InChI=1S/C14H6N2O8/c17-7-3-1-5(15(21)22)9-11(7)14(20)12-8(18)4-2-6(16(23)24)10(12)13(9)19/h1-4,17-18H

InChI key: InChIKey=GJCHQJDEYFYWER-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)C=3C1=C(N(=O)=O)C=CC3O)=C(O)C=CC2N(=O)=O

Synonyms:

• 1,8-Dihydroxy-4,5-Dinitro anthraquinone
• 1,8-Dihydroxy-4,5-Dinitro-10-Anthracenedione
• 1,8-Dihydroxy-4,5-Dinitroanthra-9,10-Quinone
• 1,8-Dihydroxy-4,5-Dinitroanthracene-9,10-Dione
• 1,8-Dihydroxy-4,5-dinitro-9,10-anthracenedione
• 1,8-Dihydroxy-4,5-dinitro-9,10-anthraquinone
• 1,8-Dinitro-4,5-dihydroxyanthraquinone
• 4,5-Dihydroxy-1,8-dinitroanthraquinone
• 4,5-Dinitrochrysazin
• 9,10-Anthracenedione, 1,8-Dihydroxy-4,5-Dinitro-
• Anthraquinone, 1,8-dihydroxy-4,5-dinitro-
• Ardp 0006
• Chrysazin, 4,5-dinitro-
• NSC 81256

9,10-Anthracenedione,1,8-dihydroxy-4,5-dinitro-

CAS: 81-55-0

Formula: C₁₄H₆N₂O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 330.2060

Ref: IN-DA00528K

ARDP0006

CAS: 81-55-0

ARDP0006

Purity: ≥95%

Molecular weight: 330.21g/mol

Ref: 54-BUP18773

1,8-Dihydroxy-4,5-Dinitroanthraquinone

CAS: 81-55-0

1,8-Dihydroxy-4,5-Dinitroanthraquinone

Purity: 98%

Molecular weight: 330.21g/mol

Ref: 54-OR1029874

1,8-DIHYDROXY-4,5-DINITROANTHRAQUINONE

CAS: 81-55-0

Purity: 95%

Molecular weight: 330.2080078125

Ref: 10-F842575

ARDP0006

CAS: 81-55-0

ARDP0006 is an inhibitor of NS2B-NS3 protease.

Formula: C₁₄H₆N₂O₈

Purity: 99.01%

Color and Shape: Physical Description Brownish Gold Solid (Ntp 1992)

Molecular weight: 330.21

Ref: TM-T19900

1,8-Dihydroxy-4,5-dinitro-9,10-anthracenedione

Controlled Product

CAS: 81-55-0

Applications 1,8-Dihydroxy-4,5-dinitro-9,10-anthracenedione is a NS2B-NS3 protease specific inhibitor that is used for treatment of Dengue and West Nile virus infections.
References Tomlinson, Suzanne M., et al.: Antivir. Res., 89(2), 127-135 (2011)

Formula: C₁₄H₆N₂O₈

Color and Shape: Neat

Molecular weight: 330.21

Ref: TR-D450190

1,8-Dihydroxy-4,5-dinitroanthraquinone

CAS: 81-55-0

1,8-Dihydroxy-4,5-dinitroanthraquinone (1,8DDNA) is a chemical inhibitor that inhibits the protease activity of ns3 protease. 1,8DDNA has been shown to inhibit the replication of wild-type virus in cell culture. This molecule also inhibits methyl transferase and structural analysis. The second-order rate constant for this compound was found to be 0.64 M-1s-1 at pH 7.5 in the presence of 10 mM NaCl and 5 mM Tris buffer at pH 8.0. 1,8DDNA's solubility data indicates that it is soluble in water with a solubility limit of 9 g/L at 25°C; however, its solubility decreases as the temperature increases.

Formula: C₁₄H₆N₂O₈

Purity: Min. 95%

Molecular weight: 330.21 g/mol

Ref: 3D-FD41685

Anthraquinone Impurity 6

CAS: 81-55-0

Formula: C₁₄H₆N₂O₈

Molecular weight: 330.21

Ref: ST-EA-CP-A130004