CAS 81-84-5

Naphthalic anhydride

Description:

Naphthalic anhydride, with the CAS number 81-84-5, is an organic compound derived from naphthalene. It appears as a white to light yellow crystalline solid and is known for its distinctive aromatic structure, which contributes to its chemical reactivity. This compound is primarily used as an intermediate in the synthesis of various chemicals, including dyes, pigments, and plasticizers. Naphthalic anhydride is characterized by its ability to undergo reactions typical of anhydrides, such as hydrolysis to form naphthalene dicarboxylic acid. It has a relatively high melting point and is soluble in organic solvents like acetone and ethanol, but insoluble in water. Due to its chemical properties, it can act as a reagent in organic synthesis, particularly in the formation of polyesters and other polymeric materials. Safety precautions are necessary when handling naphthalic anhydride, as it can be irritating to the skin, eyes, and respiratory system. Proper storage in a cool, dry place away from incompatible substances is also essential to maintain its stability.

Formula: C₁₂H₆O₃

InChI: InChI=1S/C12H6O3/c13-11-8-5-1-3-7-4-2-6-9(10(7)8)12(14)15-11/h1-6H

InChI key: InChIKey=GRSMWKLPSNHDHA-UHFFFAOYSA-N

SMILES: O=C1C=2C=3C(C(=O)O1)=CC=CC3C=CC2

Synonyms:

• 1,8-Naphthalenedicarboxylic acid anhydride
• 1,8-Naphthalenedicarboxylic anhydride
• 1,8-Naphthalic acid anhydride
• 1,8-Naphthanoic anhydride
• 1,8-Naphthoic anhydride
• 1H,3H-Naphtho[1,8-cd]pyran-1,3-dione
• Anhidrido Naftaleno-1,8-Dicarboxilico
• Anhydride naphtalene-1,8-dicarboxylique
• Naphthalene dicarboxylic anhydride
• Naphthalene-1,8-Dicarboxylic Acid Anhydride
• Naphthalene-1,8-Dicarboxylic Anhydride
• Naphthalene-2,6-dicarboxylic acid anhydride
• Naphthalic acid anhydride
• Naphthalic anhydride
• Naphthalin-1,8-dicarbonsaureanhydrid
• Nsc 5747
• Protect
• Protect (agrochemical)

1,8-Naphthalic Anhydride

CAS: 81-84-5

Formula: C₁₂H₆O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 198.18

Ref: 3B-N0022

1,8-Naphthalic anhydride, 97%

CAS: 81-84-5

1,8-Naphthalic anhydride is used as a seed protectant and to prepare dyestuffs and optical brighteners. It is used in the preparation of napthalimide analogues, which finds application as anticancer agents. Further, it is used as fluorescent brightening agent for polymeric materials. This Thermo Sci

Formula: C₁₂H₆O₃

Purity: 97%

Color and Shape: White to cream to yellow to pale brown, Powder or crystalline powder

Molecular weight: 198.18

Ref: 02-A13519

1,8-Naphthalic anhydride

CAS: 81-84-5

1,8-Naphthalic anhydride

Formula: C₁₂H₆O₃

Purity: 98%

Color and Shape: faint yellow crystalline solid

Molecular weight: 198.17g/mol

Ref: 54-OR28586

1,8-Naphthoic Anhydride

Controlled Product

CAS: 81-84-5

Applications 1,8-Naphthoic Anhydride is used in the synthesis of napthalimide analogues as anticancer agents.
References Verma, M. et al.: Eur, J, Med. Chem., 68 (2013); Quintana-E,. et al.: Bioorg, Med. Chem., 21, 6484 (2013);

Formula: C₁₂H₆O₃

Color and Shape: Neat

Molecular weight: 198.17

Ref: TR-N345300

Benzo[de]isochromene-1,3-dione

CAS: 81-84-5

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 198.177001953125

Ref: 10-F222568

1,8-Naphthalic anhydride

CAS: 81-84-5

1,8-Naphthalic anhydride is a potent inducer of dinucleotide phosphate (NADPH), which is important for the biosynthesis of fatty acids, proteins and carbohydrates. It also inhibits the enzyme activities of both antimicrobial agents and infectious diseases. 1,8-Naphthalic anhydride has been shown to be effective against solid tumours in treatment trials. This drug may lead to neuronal death by inhibiting ATP production in the mitochondria. The x-ray crystal structure shows that this drug binds to NADPH and water molecules in the active site of the enzyme, forming a covalent bond with NADPH. 1,8-Naphthalic anhydride has also been shown to have anti-inflammatory properties due to its ability to inhibit toll-like receptor 4 signaling pathways.

Formula: C₁₂H₆O₃

Purity: Min. 98 Area-%

Color and Shape: Off-White Powder

Molecular weight: 198.17 g/mol

Ref: 3D-FN00567

1,8-Naphthalic anhydride

CAS: 81-84-5

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Formula: C₁₂H₆O₃

Purity: Min. 99.0%

Molecular weight: 198.17 g/mol

Ref: 3D-Q-200092