CAS 81045-50-3

Pivopril

Description:

Pivopril is a pharmaceutical compound classified as an angiotensin-converting enzyme (ACE) inhibitor, primarily used in the treatment of hypertension and heart failure. Its chemical structure features a proline derivative, which contributes to its mechanism of action by inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This inhibition leads to vasodilation, reduced blood pressure, and decreased workload on the heart. Pivopril is characterized by its moderate solubility in water and its stability under standard conditions. The compound is typically administered in oral form and is metabolized in the liver, with its pharmacokinetics influenced by factors such as age and liver function. Common side effects may include dizziness, cough, and elevated potassium levels, similar to other ACE inhibitors. As with any medication, it is essential to monitor patients for potential adverse reactions and interactions with other drugs. Overall, Pivopril represents a valuable option in the management of cardiovascular conditions, contributing to improved patient outcomes.

Formula: C₁₆H₂₇NO₄S

InChI: InChI=1/C16H27NO4S/c1-11(10-22-15(21)16(2,3)4)14(20)17(9-13(18)19)12-7-5-6-8-12/h11-12H,5-10H2,1-4H3,(H,18,19)/t11-/m1/s1

InChI key: InChIKey=XRKXJJYSKUIIEN-LLVKDONJSA-N

SMILES: N(C([C@@H](CSC(C(C)(C)C)=O)C)=O)(CC(O)=O)C1CCCC1

Synonyms:

• 2,2-Dimethylthiopropionic acid, S-ester with (-)-(S)-N-cyclopentyl-N-(3-mercapto-2-methylpropionyl)glycine
• Glycine, N-cyclopentyl-N-(3-((2,2-dimethyl-1-oxopropyl)thio)-2-methyl-1-oxopropyl)-, (S)-(-)-
• Glycine, N-cyclopentyl-N-[(2S)-3-[(2,2-dimethyl-1-oxopropyl)thio]-2-methyl-1-oxopropyl]-
• N-Cyclopentyl-N-[(2S)-3-[(2,2-dimethyl-1-oxopropyl)thio]-2-methyl-1-oxopropyl]glycine
• N-cyclopentyl-N-{(2R)-3-[(2,2-dimethylpropanoyl)sulfanyl]-2-methylpropanoyl}glycine
• N-cyclopentyl-N-{(2S)-3-[(2,2-dimethylpropanoyl)sulfanyl]-2-methylpropanoyl}glycine
• Pivalopril
• Pivopril [USAN:INN]
• Rhc 3659(S)
• Unii-3V6I5962Em
• Pivopril

Pivopril

CAS: 81045-50-3

Pivopril is a drug used to treat high blood pressure (hypertension) and heart failure. Pivopril is classified as a vasodilator that prevents the constriction of blood vessels, which are caused by angiotensin II. It also blocks the production of fatty acids that cause inflammation in the intestines and reduces bowel motility. Pivopril has been shown to be effective in treating cancer; it inhibits the growth of cancer cells by interfering with their ability to produce proteins needed for cell division. The drug also stimulates the production of growth factors and increases metabolism in patients with metabolic disorders.

Formula: C₁₆H₂₇NO₄S

Purity: Min. 95%

Molecular weight: 329.5 g/mol

Ref: 3D-GDA04550

Pivalopril

CAS: 81045-50-3

Pivalopril is a new orally active inhibitor of angiotensin-converting enzyme.

Formula: C₁₆H₂₇NO₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 329.45

Ref: TM-T16544