CAS 81051-65-2

2-(4-chlorophenyl)-1-ethyl-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid

Description:

2-(4-Chlorophenyl)-1-ethyl-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid, with CAS number 81051-65-2, is a compound belonging to the dihydropyridine class, which is known for its role in various biological activities, particularly as calcium channel blockers. This substance features a dihydropyridine core, characterized by a pyridine ring with two hydrogen atoms replaced by an ethyl group and a methyl group, along with a carboxylic acid functional group. The presence of a 4-chlorophenyl substituent enhances its lipophilicity and may influence its pharmacological properties. Typically, compounds of this class exhibit a range of biological activities, including antihypertensive and antianginal effects. The structural features contribute to its potential interactions with biological targets, making it of interest in medicinal chemistry. Additionally, the compound's solubility, stability, and reactivity can be influenced by the functional groups present, which are critical for its application in drug development and therapeutic use.

Formula: C₁₅H₁₄ClNO₃

InChI: InChI=1S/C15H14ClNO3/c1-3-17-9(2)8-12(18)13(15(19)20)14(17)10-4-6-11(16)7-5-10/h4-8H,3H2,1-2H3,(H,19,20)

InChI key: InChIKey=GQFJDWYHPRLNHR-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(N(CC)C(C)=CC1=O)C2=CC=C(Cl)C=C2

Synonyms:

• 2-(4-Chlorophenyl)-1-ethyl-1,4-dihydro-6-methyl-4-oxo-3-pyridinecarboxylic Acid
• 2-(4-Chlorophenyl)-1-ethyl-1,4-dihydro-6-methyl-4-oxonicotinic Acid
• 2-(4-Chlorophenyl)-1-ethyl-6-methyl-4-oxo-1,4-dihydro-3-pyridinecarboxylic acid
• 3-Pyridinecarboxylic Acid, 2-(4-Chlorophenyl)-1-Ethyl-1,4-Dihydro-6-Methyl-4-Oxo-
• Karetazan
• 2-(4-Chlorophenyl)-1-ethyl-6-methyl-4-oxo-1,4-dihydropyridine-3-carboxylic acid

Karetazan 100 µg/mL in Acetonitrile

Controlled Product

CAS: 81051-65-2

Formula: C₁₅H₁₄ClNO₃

Color and Shape: Single Solution

Molecular weight: 291.73

Ref: 04-A14511000AL-100

Karetazan

CAS: 81051-65-2

Karetazan is a pesticide agent.

Formula: C₁₅H₁₄ClNO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 291.73

Ref: TM-T24248

Karetazan

Controlled Product

CAS: 81051-65-2

Applications Karetazan is used in the preparation of Pyrazole derivatives as pesticides as well as as a chemical hybridisation agent for commercial hybrid seed production.
References Buysse, A., et al.: U.S. Pat. Appl. Publ., 118 (2016); Walsh, M., et al.: U.S. Pat. Appl. Publ. 77., (2015)

Formula: C₁₅H₁₄ClNO₃

Color and Shape: White To Off-White

Molecular weight: 291.73

Ref: TR-K452255