Mal-PEG1-t-butyl ester, identified by the CAS number 810677-16-8, is a chemical compound that features a malonic acid derivative linked to a polyethylene glycol (PEG) moiety. This compound typically exhibits characteristics such as solubility in polar solvents due to the PEG segment, which enhances its hydrophilicity. The presence of the malonic acid structure allows for potential reactivity, particularly in conjugation reactions, making it useful in bioconjugation and drug delivery applications. The t-butyl ester group provides stability and protection to the carboxylic acid functionality, which can be activated under specific conditions for further chemical transformations. Overall, Mal-PEG1-t-butyl ester serves as a versatile building block in the synthesis of more complex biomolecules, facilitating the development of therapeutics and diagnostic agents. Its properties, including molecular weight and reactivity, can be tailored by modifying the PEG length or the functional groups attached, allowing for customization in various chemical and biological applications.

Mal-PEG1-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Mal-PEG1-t-butyl ester

810677-16-8: Mal-PEG1-t-butyl ester, identified by the CAS number 810677-16-8, is a chemical compound that features a malonic acid derivative linked to a polyethylene glycol (PEG) moiety. This compound typically exhibits characteristics such as solubility in polar solvents due to the PEG segment, which enhances its hydrophilicity. The presence of the malonic acid structure allows for potential reactivity, particularly in conjugation reactions, making it useful in bioconjugation and drug delivery applications. The t-butyl ester group provides stability and protection to the carboxylic acid functionality, which can be activated under specific conditions for further chemical transformations. Overall, Mal-PEG1-t-butyl ester serves as a versatile building block in the synthesis of more complex biomolecules, facilitating the development of therapeutics and diagnostic agents. Its properties, including molecular weight and reactivity, can be tailored by modifying the PEG length or the functional groups attached, allowing for customization in various chemical and biological applications.

1,1-Dimethylethyl 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]propanoate

Mal-PEG1-Boc is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

CAS 810677-16-8

Mal-PEG1-t-butyl ester

1,1-Dimethylethyl 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]propanoate

Ref: IN-DA00ID5W

Mal-PEG1-Boc

Ref: TM-T15974

Mal-PEG1-Boc

Ref: 10-F554683