The chemical substance "H-Ala-Tyr-Ala-OH," with the CAS number 81075-03-8, is a peptide composed of three amino acids: alanine (Ala), tyrosine (Tyr), and another alanine. This peptide is characterized by its structure, which includes an N-terminal amino group (H-) and a C-terminal carboxylic acid group (OH), indicating that it is a free amino acid at one end. The presence of tyrosine contributes to its potential for various biochemical interactions due to the aromatic side chain, which can participate in hydrogen bonding and π-π stacking. Peptides like H-Ala-Tyr-Ala-OH are often studied for their biological activity, stability, and potential applications in pharmaceuticals, as they can mimic natural peptides or proteins. Additionally, their solubility, hydrophobicity, and overall stability can vary based on the sequence and the environment, influencing their behavior in biological systems. Overall, this peptide serves as a model for understanding peptide interactions and functions in biological contexts.

H-Ala-Tyr-Ala-OH

81075-03-8: The chemical substance "H-Ala-Tyr-Ala-OH," with the CAS number 81075-03-8, is a peptide composed of three amino acids: alanine (Ala), tyrosine (Tyr), and another alanine. This peptide is characterized by its structure, which includes an N-terminal amino group (H-) and a C-terminal carboxylic acid group (OH), indicating that it is a free amino acid at one end. The presence of tyrosine contributes to its potential for various biochemical interactions due to the aromatic side chain, which can participate in hydrogen bonding and π-π stacking. Peptides like H-Ala-Tyr-Ala-OH are often studied for their biological activity, stability, and potential applications in pharmaceuticals, as they can mimic natural peptides or proteins. Additionally, their solubility, hydrophobicity, and overall stability can vary based on the sequence and the environment, influencing their behavior in biological systems. Overall, this peptide serves as a model for understanding peptide interactions and functions in biological contexts.

<p>H-Ala-Tyr-Ala-OH is a peptidomimetic that has shown promising anti-inflammatory and anticancer properties. It has been found to inhibit the proliferation of human cancer cells and to suppress the growth of human tumor xenografts in mice. It also has shown an ability to cross the blood brain barrier, which may be due to its high lipophilicity. H-Ala-Tyr-Ala-OH inhibits the production of inflammatory cytokines, such as TNFα, IL1β, IL6, and IL8, by inhibiting NFκB activation in immune cells. This inhibition leads to decreased inflammation and fibrosis in various tissues. H-Ala-Tyr-Ala-OH is also active against bacteria and viruses, which may be due to its low molecular weight.</p>

CAS 81075-03-8

H-Ala-Tyr-Ala-OH

H-Ala-Tyr-Ala-OH

Ref: 3D-FA107980