CAS 81115-60-8

1H-Indazol-4-amine, 5-methyl-

Description:

1H-Indazol-4-amine, 5-methyl- (CAS 81115-60-8) is a chemical compound characterized by its indazole core, which consists of a five-membered ring containing two nitrogen atoms. This compound features an amino group (-NH2) at the 4-position and a methyl group (-CH3) at the 5-position of the indazole ring. The presence of the amino group contributes to its potential as a building block in medicinal chemistry, as it can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. The methyl substitution can influence the compound's solubility, stability, and biological activity. Typically, compounds like 1H-Indazol-4-amine, 5-methyl- are studied for their pharmacological properties, including potential anti-cancer or anti-inflammatory activities. Its structural characteristics suggest that it may interact with biological targets, making it of interest in drug discovery and development. As with many organic compounds, its physical properties, such as melting point, boiling point, and solubility, would depend on the specific conditions and purity of the sample.

Formula: C₈H₉N₃

5-Methyl-1H-indazol-4-amine

CAS: 81115-60-8

Formula: C₈H₉N₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 147.1772

Ref: IN-DA004ZR8

5-Methyl-1H-indazol-4-amine

CAS: 81115-60-8

5-Methyl-1H-indazol-4-amine

Formula: C₈H₉N₃

Purity: 95%

Color and Shape: brown solid

Molecular weight: 147.18g/mol

Ref: 54-OR305526

5-Methyl-1H-indazol-4-amine

CAS: 81115-60-8

Formula: C₈H₉N₃

Purity: 95%

Molecular weight: 147.181

Ref: 10-F498034

5-Methyl-1H-indazol-4-amine

CAS: 81115-60-8

5-Methyl-1H-indazol-4-amine is a tyrosine kinase inhibitor that has been shown to be potent in inhibiting the activity of various types of tyrosine kinases. It has good oral pharmacokinetics and is not metabolized by the liver. 5-Methyl-1H-indazol-4-amine binds to the ATP site on the enzyme and prevents phosphorylation, which inhibits cell proliferation and growth. This agent also inhibits DNA synthesis, protein synthesis, and phosphoinositide turnover in cells. 5-Methyl-1H-indazol-4-amine is an orally active inhibitor of tyrosine kinases with good oral pharmacokinetics and does not require metabolic activation by the liver. This agent may be used for the treatment of cancer or other diseases associated with uncontrolled cell growth.

Formula: C₈H₉N₃

Purity: Min. 95%

Molecular weight: 147.18 g/mol

Ref: 3D-GDA11560