CAS 81117-35-3

2-(hydroxymethyl)-1-nonylpiperidine-3,4,5-triol

Description:

2-(Hydroxymethyl)-1-nonylpiperidine-3,4,5-triol, with the CAS number 81117-35-3, is a chemical compound characterized by its piperidine ring structure, which is a six-membered nitrogen-containing heterocycle. This compound features a nonyl group, indicating a long hydrophobic carbon chain, which contributes to its lipophilicity. The presence of three hydroxyl (-OH) groups at the 3, 4, and 5 positions of the piperidine ring suggests that it has significant hydrophilicity, allowing for potential interactions with water and biological systems. The hydroxymethyl group at the 2-position further enhances its reactivity and solubility in polar solvents. Due to its unique structure, this compound may exhibit interesting biological activities, potentially serving as a surfactant or in pharmaceutical applications. Its properties, such as solubility, stability, and reactivity, can be influenced by the balance between the hydrophobic nonyl chain and the hydrophilic hydroxyl groups, making it a compound of interest in various chemical and biological contexts.

Formula: C₁₅H₃₁NO₄

InChI: InChI=1/C15H31NO4/c1-2-3-4-5-6-7-8-9-16-10-13(18)15(20)14(19)12(16)11-17/h12-15,17-20H,2-11H2,1H3

SMILES: CCCCCCCCCN1CC(C(C(C1CO)O)O)O

Synonyms:

• 3,4,5-Piperidinetriol, 2-(Hydroxymethyl)-1-Nonyl-

N-(n-Nonyl)deoxynojirimycin

CAS: 81117-35-3

Formula: C₁₅H₃₁NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 289.4109

Ref: IN-DA008L6M

N-(n-Nonyl)-1-deoxynojirimycin

CAS: 81117-35-3

N-(n-Nonyl)-1-deoxynojirimycin

Purity: >99%

Color and Shape: white crystalline solid

Molecular weight: 289.41g/mol

Ref: 54-BICL4182

N-Nonyldeoxynojirimycin

CAS: 81117-35-3

N-Nonyldeoxynojirimycin (NN-DNJ) is an inhibitor of acid α-glucosidase and α-1,6-glucosidase (IC50s = 0.42 and 8.4 μM, respectively).

Formula: C₁₅H₃₁NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 289.41

Ref: TM-TP1080

N-Nonyldeoxynojirimycin

CAS: 81117-35-3

Ref: 7W-GC6918

N-(n-Nonyl)deoxynojirimycin

Controlled Product

CAS: 81117-35-3

Applications An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. A possible therapeutic agent for Gaucher disease.
References Sawkar. A.R., et al.: P. Natl. Acad. Sci., 99, 24, 15428 (2002)

Formula: C₁₅H₃₁NO₄

Color and Shape: Neat

Molecular weight: 289.41

Ref: TR-N650300

N-Nonyldeoxynojirimycin

CAS: 81117-35-3

Inhibitor and pharmacological chaperone of lysosomal β-glucosidase (glucosylceramidase). The compound binds to the unstable glucosidase active site during the folding and post-translational processing in Golgi apparatus and endoplasmatic reticulum. It is effective in stabilising the enzyme and preventing accumulation of glucosylceramides in models for Gaucher disease, especially in the ones carrying N370S mutation. In addition, it has antiviral activity against Hepatitis C virus, which is mediated by misfolding of viral glycoproteins in the presence of the inhibitor.

Formula: C₁₅H₃₁NO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 289.41 g/mol

Ref: 3D-MN04790