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CAS 81144-43-6

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5'-O-(4,4'-dimethoxytrityl)-2'-*deoxyguanosine

Description:
5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine is a modified nucleoside that plays a significant role in biochemistry, particularly in the synthesis of oligonucleotides. This compound features a deoxyguanosine base, which is one of the four nucleobases in DNA, and is modified at the 5' position with a dimethoxytrityl (DMT) protecting group. The DMT group is commonly used in solid-phase DNA synthesis to protect the 5' hydroxyl group, preventing premature reactions during the synthesis process. The presence of the dimethoxy groups enhances the stability and solubility of the compound. This nucleoside is typically used in the synthesis of DNA strands, where it serves as a building block for the incorporation of guanine residues. Its chemical structure allows for specific interactions with complementary nucleobases, making it essential for the formation of stable DNA duplexes. Overall, 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine is a crucial component in molecular biology applications, particularly in the fields of genetic engineering and therapeutic development.
Formula:C31H31N5O6
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Found 2 products.
  • 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyguanosine
    Apollo Scientific
    + Info

    5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyguanosine

    CAS:
    <p>5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyguanosine</p>
    Formula:C31H31N5O6
    Purity:98%
    Color and Shape: white solid
    Molecular weight:569.61g/mol

    Ref: 54-OR926427

    1g
    426.00€
    250mg
    170.00€
  • 2'-Deoxy-5'-O-DMT-guanosine
    Biosynth
    + Info

    2'-Deoxy-5'-O-DMT-guanosine

    CAS:
    <p>2'-Deoxy-5'-O-DMT-guanosine is a purine nucleoside that is converted to 2'-deoxy-5'-O-DMT-adenosine by the enzyme deoxyadenosyltransferase. This conversion is necessary for the synthesis of adenosylcobalamin, which is essential for the methylation of homocysteine to methionine. 2'-Deoxy-5'-O-DMT-guanosine has been shown to have cancer chemopreventive effects in vitro and in vivo. It also has been shown to enhance dna hybridization and hydrophobic interactions with cancerous cells, which may be due to its ability to inhibit gene expression.</p>
    Formula:C31H31N5O6
    Purity:Min. 95%
    Molecular weight:569.61 g/mol

    Ref: 3D-ND57359

    1g
    303.00€