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CAS 81147-92-4

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Esmolol

Description:
Esmolol is a selective beta-1 adrenergic antagonist primarily used in clinical settings for the management of tachycardia and hypertension, particularly in acute situations. It is characterized by its rapid onset and short duration of action, making it suitable for intravenous administration in emergency scenarios. The chemical structure of esmolol features an ethylamino group and a phenolic moiety, contributing to its pharmacological properties. Its rapid metabolism is primarily due to hydrolysis by red blood cell esterases, which allows for quick termination of its effects once the infusion is stopped. Esmolol is often preferred in situations where precise control of heart rate is necessary, such as during surgery or in critically ill patients. Additionally, it has a favorable side effect profile, with fewer respiratory effects compared to non-selective beta-blockers, making it a safer option for patients with respiratory conditions. Overall, esmolol's unique characteristics make it a valuable tool in acute cardiovascular management.
Formula:C16H25NO4
InChI:InChI=1S/C16H25NO4/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3
InChI key:InChIKey=AQNDDEOPVVGCPG-UHFFFAOYSA-N
SMILES:O(CC(CNC(C)C)O)C1=CC=C(CCC(OC)=O)C=C1
Synonyms:
  • 3-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)propionic acid methyl ester
  • 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester
  • Asl 8052-001
  • Benzenepropanoic acid, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, methyl ester
  • Methyl 3-[4-(2-hydroxy-3-propan-2-ylamino-propoxy)phenyl]propanoate
  • Methyl 3-{4-[2-Hydroxy-3-(Propan-2-Ylamino)Propoxy]Phenyl}Propanoate Hydrochloride (1:1)
  • Methyl 4-[2-hydoxy-3[(1-methylethyl)amino]-propoxy]benzenepropanoate
  • (±)-Esmolol
  • Esmolol
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Found 4 products.