CAS 81213-52-7

(1-Oxyl-2,2,5,5-tetramethyl-Δ3-pyrroline-3-methyl)methanethiosulfonate

Description:

(1-Oxyl-2,2,5,5-tetramethyl-Δ3-pyrroline-3-methyl)methanethiosulfonate, commonly referred to as a nitroxide compound, is characterized by its stable free radical structure, which is derived from a pyrroline ring. This compound features a nitroxide functional group, contributing to its unique reactivity and stability under various conditions. It is often utilized in biochemical and biophysical studies, particularly in electron paramagnetic resonance (EPR) spectroscopy, due to its ability to act as a spin label. The presence of the methanethiosulfonate moiety enhances its solubility and reactivity, allowing for conjugation with biomolecules, such as proteins and nucleic acids. This property makes it valuable in the development of bioconjugates and in studying molecular interactions. Additionally, the compound's stability and radical nature make it useful in various applications, including antioxidant studies and as a probe in redox biology. Overall, its distinctive structural features and functional capabilities make it a significant tool in chemical and biological research.

Formula: C₁₀H₁₈NO₃S₂

InChI: InChI=1/C10H18NO3S2/c1-9(2)6-8(7-15-16(5,13)14)10(3,4)11(9)12/h6H,7H2,1-5H3

InChI key: InChIKey=BLSCGBLQCTWVPO-UHFFFAOYSA-N

SMILES: CC1(C)C=C(CSS(=O)(=O)C)C(C)(C)N1O

Synonyms:

• 2,5-Dihydro-2,2,5,5-tetramethyl-3-[[(methylsulfonyl)thio]methyl]-1H-pyrrol-1-yloxy
• MTSL
• 1H-Pyrrol-1-yloxy, 2,5-dihydro-2,2,5,5-tetramethyl-3-[[(methylsulfonyl)thio]methyl]-
• MTS (spin label)
• MTS

MTSL

CAS: 81213-52-7

Formula: C₁₀H₁₈NO₃S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 264.3848

Ref: IN-DA008KZG

MTSL (S-(2,2,5,5-Tetramethyl-2,5-Dihydro-1H-Pyrrol-3yl)methyl Methanesulfonothioate)

CAS: 81213-52-7

Formula: C₁₀H₁₈NO₃S₂

Color and Shape: Pale Yellow Solid

Molecular weight: 264.39

Ref: 4Z-M-099001

MTSSL

CAS: 81213-52-7

MTSSL

Purity: 97%

Ref: 54-OR1037884

MTSSL

CAS: 81213-52-7

Formula: C₁₀H₁₈NO₃S₂

Purity: ≥ 99.0%

Color and Shape: Light yellow to brown crystalline solid

Molecular weight: 264.3

Ref: 7W-GL1695

(1-Oxyl-2,2,5,5-tetramethyl-δ-3-pyrroline-3-methyl) Methanethiosulfonate

CAS: 81213-52-7

Stability Light Sensitive
Applications A highly reactive thiol-specific spin-label. A specific conformational probe of thiol site structure by virtue of its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study.
References Huang, H., et al.: Biochem., 47, 12380 (2008), Antoniou, C., et al.: Anal. Biochem., 376, 160 (2008), Padmavathi, P., et al.: J. Mol. Biol., 378, 204 (2008),

Formula: C₁₀H₁₈NO₃S₂

Color and Shape: Neat

Molecular weight: 264.38

Ref: TR-O875000

MTSSL

CAS: 81213-52-7

Trimethylethylthiosulfonate is a fatty acid derivative that has been shown to have antiatherogenic properties. It has been shown to inhibit the oxidation of low-density lipoproteins (LDLs) and the formation of foam cells, which are cells that accumulate in the vascular system and contribute to atherosclerosis. Trimethylethylthiosulfonate is also a potent nicotinic acetylcholine receptor agonist, which has been shown to increase transportan activity by increasing the number of nicotinic acetylcholine receptors. This drug has been shown to be effective in knockout mice models with dysfunctional or absent nicotinic acetylcholine receptors. Trimethylethylthiosulfonate may be used as a dietary supplement for weight loss and as an aid for weight control.

Formula: C₁₀H₁₈NO₃S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 264.39 g/mol

Ref: 3D-GDA21352

MTSSL

CAS: 81213-52-7

Purity: 97%

Color and Shape: Solid

Molecular weight: 264.3800049

Ref: 10-F863206