CAS 81226-60-0

4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol

Description:

4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol, with the CAS number 81226-60-0, is a chemical compound characterized by its complex structure, which includes a piperidine ring, an indole moiety, and a chlorophenyl group. This compound typically exhibits properties associated with both piperidine and indole derivatives, such as potential biological activity, including interactions with neurotransmitter systems. The presence of the chlorophenyl group may enhance lipophilicity, influencing its pharmacokinetic properties. The compound is often studied for its potential therapeutic applications, particularly in the fields of neuroscience and medicinal chemistry, due to its ability to modulate various biological pathways. Its solubility, stability, and reactivity can vary based on environmental conditions and the presence of other functional groups. As with many organic compounds, safety and handling precautions are essential, particularly in laboratory settings, to mitigate any potential hazards associated with its use.

Formula: C₂₀H₂₁ClN₂O

InChI: InChI=1/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2

InChI key: InChIKey=LLBLNMUONVVVPG-UHFFFAOYSA-N

SMILES: C(C=1C=2C(NC1)=CC=CC2)N3CCC(O)(CC3)C4=CC=C(Cl)C=C4

Synonyms:

• (+/-)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole
• 4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol
• 4-Piperidinol, 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-
• L 741
• L 741626
• 4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)piperidin-4-ol
• 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole
• 4-(4-CHLOROPHENYL)-1-(1H-INDOL-3-YL METHYL)PIPERIDIN-4-OL
• receptor,selective,TNF-α,Inhibitor,dopamine,Dopamine Receptor,production,L-741626,L 741626,L741626,inhibit

L-741626

CAS: 81226-60-0

L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3

Formula: C₂₀H₂₁ClN₂O

Purity: 98.57%

Color and Shape: Solid

Molecular weight: 340.85

Ref: TM-T15686

L 741626

CAS: 81226-60-0

Formula: C₂₀H₂₁ClN₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 340.8465

Ref: IN-DA00GA5B

L-741626

CAS: 81226-60-0

L-741626

Purity: ≥98%

Molecular weight: 340.85g/mol

Ref: 54-BUP10370

L-741,626

CAS: 81226-60-0

Formula: C₂₀H₂₁ClN₂O

Purity: ≥ 97.0%

Color and Shape: White to beige powder

Molecular weight: 340.85

Ref: 7W-GL4352

L-741626

Controlled Product

CAS: 81226-60-0

Formula: C₂₀H₂₁ClN₂O

Color and Shape: Neat

Molecular weight: 340.846

Ref: TR-L009520

L-741626

CAS: 81226-60-0

L-741626 is a dopamine receptor agonist that binds to the D2 dopamine receptor. It has been shown to reduce levels of dopamine in the body, which may be due to its ability to inhibit fatty acid production. L-741626 may be useful for diagnosing neurologic disorders such as Parkinson's disease and depression. L-741626 also has a hypoglycemic effect and increases calcium levels in cells. The drug has been shown to have low toxicity in animal studies and has been used as an anti-cancer agent. In addition, L-741626 is able to decrease locomotor activity and pain responses in animal models.

Formula: C₂₀H₂₁ClN₂O

Purity: Min. 95%

Molecular weight: 340.85 g/mol

Ref: 3D-GDA22660