CAS 81246-79-9

5′-O-[Bis(4-methoxyphenyl)phenylmethyl]uridine

Description:

5′-O-[Bis(4-methoxyphenyl)phenylmethyl]uridine is a modified nucleoside that features a uridine base linked to a bis(4-methoxyphenyl)phenylmethyl group at the 5′ position. This compound is characterized by its unique structural modifications, which enhance its solubility and stability compared to unmodified nucleosides. The presence of methoxy groups on the phenyl rings contributes to its electronic properties, potentially influencing its interactions in biological systems. This modification can also affect its binding affinity to nucleic acid targets, making it of interest in medicinal chemistry and drug design. The compound may exhibit unique pharmacological properties, including potential antiviral or anticancer activities, due to its structural characteristics. Additionally, its synthesis typically involves organic reactions that require careful control of conditions to ensure the integrity of the nucleoside structure. Overall, 5′-O-[Bis(4-methoxyphenyl)phenylmethyl]uridine represents a valuable tool in the study of nucleoside analogs and their applications in biochemistry and pharmacology.

Formula: C₃₀H₃₀N₂O₈

InChI: InChI=1S/C30H30N2O8/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-26(34)27(35)28(40-24)32-17-16-25(33)31-29(32)36/h3-17,24,26-28,34-35H,18H2,1-2H3,(H,31,33,36)/t24-,26-,27-,28-/m1/s1

InChI key: InChIKey=PCFSNQYXXACUHM-YULOIDQLSA-N

SMILES: C(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C(=O)NC(=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5

Synonyms:

• Uridine, 5′-O-[α,α-bis(p-methoxyphenyl)benzyl]-
• 5′-O-[Bis(4-methoxyphenyl)phenylmethyl]uridine
• 5′-Dimethoxytrityluridine
• Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-
• 5′-O-(4,4′-Dimethoxytrityl)uridine
• 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione
• 5'-O-DMTr-uridine
• 5'-O-DMT-uridine
• DMT-Ur
• 5'-O-(4,4'-DiMethyltrityl) uridine
• DTN-004 5'-O-(DiMethoxytrityl)-uridine
• DMT-RIBOURIDINE
• 5'-O-(DIMETHOXYTRITYL)-URIDINE
• 5'-O-[Bis(4-methoxy-phenyl)phenylmethyl]-uridine
• 5'-DMT -rU

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-

CAS: 81246-79-9

Formula: C₃₀H₃₀N₂O₈

Purity: 95%

Color and Shape: Solid

Molecular weight: 546.5678

Ref: IN-DA00ID69

5''-O-DMT-uridine

CAS: 81246-79-9

Ref: 7W-GN5833

5'-O-DMT-rU

CAS: 81246-79-9

5'-O-DMT-rU

Purity: ≥95%

Molecular weight: 546.57g/mol

Ref: 54-OR1005567

5'-O-DMT-rU

CAS: 81246-79-9

5’-O-DMT-rU is a modified nucleoside and can be used to synthesize RNA.

Formula: C₃₀H₃₀N₂O₈

Color and Shape: Solid

Molecular weight: 546.57

Ref: TM-T37141

5'-O-DMT-uridine

CAS: 81246-79-9

5'-O-DMT-uridine is an oligodeoxynucleotide that has been conjugated to tetracycline. It is a bioconjugate that can be used for photooxidation of DNA, as well as for the prevention of bacterial efflux. The 5'-O-DMT group can be removed from the uridine by light irradiation or by bioconjugate chemistry, which results in the release of tetracycline and subsequent binding to bacterial ribosomes. This prevents protein synthesis and cell division. The linker can be any cyclic or dehydrating compound.

Formula: C₃₀H₃₀N₂O₈

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 546.58 g/mol

Ref: 3D-ND08927

5′-O-(4,4′-DIMETHOXYTRITYL)URIDINE

CAS: 81246-79-9

Purity: 98%

Molecular weight: 546.5759888

Ref: 10-F811034

5-O-(4,4-Dimethoxytrityl)uridine

CAS: 81246-79-9

Formula: C₃₀H₃₀N₂O₈

Molecular weight: 546.58

Ref: ST-EA-CP-A88090