CAS 81246-81-3

5'-DMT-3'-TBDMS-rU

Description:

5'-DMT-3'-TBDMS-rU, also known as 5'-dimethoxytrityl-3'-tert-butyldimethylsilyl-uridine, is a modified nucleoside that plays a significant role in nucleic acid chemistry, particularly in the synthesis of RNA. This compound features a dimethoxytrityl (DMT) protecting group at the 5' position, which is commonly used to prevent unwanted reactions during oligonucleotide synthesis. The 3' position is protected by a tert-butyldimethylsilyl (TBDMS) group, which provides stability and protects the hydroxyl group from deprotonation and subsequent reactions. The uridine base contributes to the nucleoside's ability to participate in base pairing and incorporation into RNA strands. The presence of these protective groups allows for selective reactions during synthesis, making it a valuable intermediate in the production of RNA oligonucleotides. Additionally, the compound's stability and solubility characteristics are influenced by the bulky TBDMS group, which can affect its reactivity and interactions in biochemical applications. Overall, 5'-DMT-3'-TBDMS-rU is an important tool in the field of molecular biology and synthetic chemistry.

Formula: C₃₆H₄₄N₂O₈Si

Synonyms:

• 5'-O-(4,4'-DiMethoxytrityl)-3'-O-t-butyldiMethylsilyl uridine

5'-O-(4,4'-DiMethoxytrityl)-3'-O-t-butyldiMethylsilyl uridine

CAS: 81246-81-3

Formula: C₃₆H₄₄N₂O₈Si

Purity: 95%

Color and Shape: Solid

Molecular weight: 660.8287

Ref: IN-DA00G82R

1-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-3-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS: 81246-81-3

1-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-3-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Purity: 95%

Molecular weight: 660.84g/mol

Ref: 54-OR1045578

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine

CAS: 81246-81-3

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine is a nucleoside that is modified with a tert-butyldimethylsilyl group at the 3' position. It is used as an activator for synthesizing oligonucleotides, ribonucleosides, and phosphoramidites. 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine has antiviral and anticancer properties. This product can be used in research applications such as the synthesis of novel DNA and RNA molecules, as well as for diagnostic purposes such as detecting viral infections.

Formula: C₃₆H₄₄N₂O₈Si

Purity: Min. 95%

Molecular weight: 660.83 g/mol

Ref: 3D-NB33743