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CAS 81246-82-4

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5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyladenosine

Description:
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyladenosine is a modified nucleoside that features a benzoyl group at the N6 position of the adenine base and a dimethoxytrityl (DMT) protecting group at the 5' hydroxyl position. This compound is primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. The DMT group serves as a protective moiety that prevents unwanted reactions during the synthesis process, allowing for selective deprotection at specific stages. The presence of the benzoyl group enhances the stability and solubility of the nucleoside, making it suitable for various biochemical applications. Additionally, the compound exhibits characteristics typical of purine nucleosides, including the ability to participate in hydrogen bonding and base pairing, which is crucial for its role in nucleic acid structures. Overall, 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyladenosine is an important building block in the synthesis of modified RNA and DNA sequences, contributing to advancements in molecular biology and therapeutic development.
Formula:C38H35N5O7
Synonyms:
  • N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine
  • N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]adenosine
  • 5'-Dmt-Ribo Adenosine (N-Bz)
  • 5'-O-DMTr-N6-benzoyladenosine
  • N-[9-[5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]purin-6-yl]benzamide
  • N6-BENZOYL-5'-O-(DIMETHOXYTRITYL)-ADENOSINE
  • DTN-006 5'-O-(4,4'-DiMethoxytrityl)-N6-benzoyl-adenosine
  • 5'-O-(4,4'-DIMETHOXYTRITYL)-N6-BENZOYL-ADENOSINE
  • N6-Benzoyl-5'-O-DMT-adenosine
  • N6-Bz-DMT-Ar
  • See more synonyms
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