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CAS 81256-87-3

:

2'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N4-benzyl cytidine

Description:
2'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N4-benzyl cytidine is a modified nucleoside that features several distinctive characteristics. This compound is a derivative of cytidine, which is one of the four nucleosides that make up RNA. The presence of the t-butyldimethylsilyl (TBDMS) group at the 2' position enhances the stability and solubility of the molecule, making it useful in various synthetic applications. The 5'-O-(4,4'-dimethoxytrityl) group serves as a protecting group that facilitates the selective functionalization of the nucleoside during chemical synthesis, particularly in oligonucleotide synthesis. The N4-benzyl substitution provides additional steric bulk and can influence the compound's interaction with other molecules, potentially affecting its biological activity. Overall, this compound is significant in the field of nucleic acid chemistry, particularly for its utility in the synthesis of modified oligonucleotides and its potential applications in therapeutic and diagnostic contexts.
Formula:C43H49N3O8Si
Synonyms:
  • 5'-Dmt-2'-Tbdms-Bz-Rc
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