CAS 81256-89-5

5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-3′-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine

Description:

The chemical substance known as "5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-3′-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine," with the CAS number 81256-89-5, is a modified nucleoside derivative of guanosine. This compound features several notable characteristics, including the presence of a guanine base, a ribose sugar, and various functional groups that enhance its chemical stability and solubility. The modifications, such as the bis(4-methoxyphenyl)phenylmethyl and dimethylsilyl groups, contribute to its potential applications in medicinal chemistry and biochemistry, particularly in the development of nucleoside analogs for therapeutic purposes. The presence of bulky substituents may influence its interaction with biological targets, such as enzymes or receptors, and could affect its pharmacokinetic properties. Overall, this compound exemplifies the structural complexity often found in synthetic nucleoside derivatives, which are designed to improve efficacy and reduce side effects in pharmaceutical applications.

Formula: C₄₁H₅₁N₅O₈Si

InChI: InChI=1S/C41H51N5O8Si/c1-25(2)36(48)44-39-43-35-32(37(49)45-39)42-24-46(35)38-33(47)34(54-55(8,9)40(3,4)5)31(53-38)23-52-41(26-13-11-10-12-14-26,27-15-19-29(50-6)20-16-27)28-17-21-30(51-7)22-18-28/h10-22,24-25,31,33-34,38,47H,23H2,1-9H3,(H2,43,44,45,48,49)/t31-,33-,34-,38-/m1/s1

InChI key: InChIKey=XAIQBZNFPUNWMQ-CJEGOSRCSA-N

SMILES: C(OC[C@@H]1[C@@H](O[Si](C(C)(C)C)(C)C)[C@@H](O)[C@@H](O1)N2C3=C(N=C2)C(=O)N=C(NC(C(C)C)=O)N3)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6

Synonyms:

• 5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-3′-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine
• Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine

CAS: 81256-89-5

Formula: C₄₁H₅₁N₅O₈Si

Purity: 97%

Color and Shape: Solid

Molecular weight: 769.9578

Ref: IN-DA01E9T9

5'-Dmt-3'-Tbdms-Ibu-Rg

CAS: 81256-89-5

5'-Dmt-3'-Tbdms-Ibu-Rg

Purity: 98%

Molecular weight: 769.96g/mol

Ref: 54-OR1026397

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine

CAS: 81256-89-5

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine is a deoxyribonucleoside that is chemically modified to be resistant to nucleases. It is used as an antiviral agent and activates the immune system by inducing cytokines, chemokines, and interferons. 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine has been shown to have antidepressant effects in mice and rats. This drug also has been shown to inhibit the production of HIV viral particles in vitro.

Formula: C₄₁H₅₁N₅O₈Si

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 769.96 g/mol

Ref: 3D-NB33744

5′-DMT-3′-TBDMS-ibu-rG

CAS: 81256-89-5

Purity: 98%

Color and Shape: Solid

Molecular weight: 769.971

Ref: 10-F986825

5'-DMT-3'-TBDMS-ibu-rG

CAS: 81256-89-5

5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.

Formula: C₄₁H₅₁N₅O₈Si

Color and Shape: Solid

Molecular weight: 769.96

Ref: TM-T40919