CAS 81276-03-1

14,15-Epoxyeicosatrienoic acid

Description:

14,15-Epoxyeicosatrienoic acid (14,15-EET) is a bioactive lipid derived from arachidonic acid, characterized by its epoxide functional group. It is part of the eicosanoid family, which plays crucial roles in various physiological processes, including inflammation, vascular function, and cell signaling. The compound is known for its potent vasodilatory effects, contributing to the regulation of blood pressure and promoting endothelial function. 14,15-EET is produced through the action of cytochrome P450 enzymes, specifically CYP2C and CYP2J subfamilies, which convert arachidonic acid into epoxyeicosatrienoic acids. This substance exhibits various biological activities, including anti-inflammatory properties and the ability to influence cellular proliferation and apoptosis. Additionally, it has been implicated in neuroprotection and the modulation of pain pathways. Due to its diverse roles in human physiology, 14,15-EET is a subject of interest in pharmacological research, particularly in the context of cardiovascular health and potential therapeutic applications.

Formula: C₂₀H₃₂O₃

InChI: InChI=1S/C20H32O3/c1-2-3-12-15-18-19(23-18)16-13-10-8-6-4-5-7-9-11-14-17-20(21)22/h4,6-7,9-10,13,18-19H,2-3,5,8,11-12,14-17H2,1H3,(H,21,22)

InChI key: InChIKey=JBSCUHKPLGKXKH-UHFFFAOYSA-N

SMILES: C(C=CCC=CCC=CCCCC(O)=O)C1C(CCCCC)O1

Synonyms:

• 13-(3-Pentyl-2-oxiranyl)-5,8,11-tridecatrienoic acid
• 14,15-Epoxyeicosatrienoic acid
• 14,15-Epoxyeicosa-5,8,11-trienoic acid
• 5,8,11-Tridecatrienoic acid, 13-(3-pentyl-2-oxiranyl)-
• 5,8,11-Tridecatrienoic acid, 13-(3-pentyloxiranyl)-

14(15)-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid

Controlled Product

CAS: 81276-03-1

Formula: C₂₀H₃₂O₃

Color and Shape: Neat

Molecular weight: 336.47

Ref: TR-E350670

14,15-Epoxyeicosatrienoic acid

CAS: 81276-03-1

14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances

Formula: C₂₀H₃₂O₃

Color and Shape: Solid

Molecular weight: 320.47

Ref: TM-T83451