CAS 813-77-4

dimethyl chlorophosphate

Description:

Dimethyl chlorophosphate, with the CAS number 813-77-4, is an organophosphorus compound characterized by its chemical structure, which includes two methyl groups and a chlorophosphate functional group. It is a colorless to pale yellow liquid with a pungent odor, and it is known for its high reactivity, particularly due to the presence of the chlorophosphate moiety. This compound is primarily used as an intermediate in the synthesis of various chemicals, including pesticides and pharmaceuticals. It is also recognized for its potential as a chemical warfare agent, which raises concerns regarding its toxicity and environmental impact. Dimethyl chlorophosphate is soluble in organic solvents but has limited solubility in water. Safety precautions are essential when handling this substance, as it can be harmful if inhaled, ingested, or absorbed through the skin. Proper storage and disposal methods are crucial to mitigate risks associated with its use.

Formula: C₂H₆ClO₃P

InChI: InChI=1/C2H6ClO3P/c1-5-7(3,4)6-2/h1-2H3

SMILES: COP(=O)(Cl)OC

Synonyms:

• Phosphorochloridic acid, dimethyl ester
• Methyl phosphorochloridate
• Dimethyl Phosphorochloridate

Dimethyl Chlorophosphate

CAS: 813-77-4

Formula: C₂H₆ClO₃P

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 144.49

Ref: 3B-D5601

Dimethyl Phosphorochloridate (90%)

Controlled Product

CAS: 813-77-4

Stability Moisture Sensitive
Applications A phosphorylating agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sartori, et al.: Chem. Rev., 48, (1951), Nachmansohn, et al.: Adv. Enzymology, 12, 259 (1951)

Formula: C₂H₆ClO₃P

Purity: 90%

Color and Shape: Neat

Molecular weight: 144.494

Ref: TR-D813775

Dimethyl phosphorochloridate

CAS: 813-77-4

Dimethyl phosphorochloridate is an organophosphorus compound that inhibits the growth of bacteria by binding to the 50S ribosomal subunit. The drug binds to the 3'-terminal adenosine residue in 16S ribosomal RNA and prevents protein synthesis, leading to cell death. Dimethyl phosphorochloridate has been shown to be effective against autoimmune diseases such as rheumatoid arthritis and Crohn's disease. This drug also increases the production of growth factors, which may be due to its ability to inhibit prostaglandin synthesis. The mechanism by which this drug inhibits bacterial growth remains unclear. Dimethyl phosphorochloridate has been shown to act as a nucleophile in cationic polymerization reactions with amides and malonic acid. It reacts with trimethyl copper chloride (TMC) under basic conditions in a model system, producing a signal pathway that leads to hydrogen bond formation between the hydroxyl group and TMC.

Formula: C₂H₆ClO₃P

Purity: Min. 95%

Color and Shape: Colourless To Pale Yellow Clear Liquid

Molecular weight: 144.49 g/mol

Ref: 3D-FD22255

Dimethyl phosphorochloridate

CAS: 813-77-4

Formula: C₂H₆ClO₃P

Purity: 97%

Color and Shape: Liquid

Molecular weight: 144.4940

Ref: IN-DA0034R9