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CAS 81329-71-7

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Modecainide

Description:
Modecainide is a chemical compound classified as an antiarrhythmic agent, primarily used in the treatment of cardiac arrhythmias. It is a member of the class 1C antiarrhythmics, which work by blocking sodium channels in cardiac tissues, thereby stabilizing the cardiac membrane and reducing excitability. Modecainide is characterized by its ability to prolong the refractory period of cardiac action potentials, which helps to restore normal rhythm in the heart. The compound is typically administered in its hydrochloride salt form and is known for its moderate potency and efficacy in managing various types of arrhythmias. Its chemical structure includes a piperidine ring, contributing to its pharmacological properties. Modecainide may exhibit side effects common to antiarrhythmic medications, such as dizziness, fatigue, or gastrointestinal disturbances. Due to its specific action on cardiac tissues, careful monitoring is essential during its use to avoid potential adverse effects, particularly in patients with pre-existing heart conditions. As with all medications, it is crucial to follow medical guidance regarding its use and dosage.
Formula:C22H28N2O3
InChI:InChI=1S/C22H28N2O3/c1-24-14-6-5-8-18(24)12-10-16-7-3-4-9-19(16)23-22(26)17-11-13-20(25)21(15-17)27-2/h3-4,7,9,11,13,15,18,25H,5-6,8,10,12,14H2,1-2H3,(H,23,26)
InChI key:InChIKey=LBYXPDAENJSHDD-UHFFFAOYSA-N
SMILES:C(CC1N(C)CCCC1)C2=C(NC(=O)C3=CC(OC)=C(O)C=C3)C=CC=C2
Synonyms:
  • (+-)-2'-(2-(1-Methyl-2-piperidyl)ethyl)vanillanilide
  • (+-)-4-Hydroxy-3-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide
  • 3-Methoxy-O-demethyl encainide
  • 3-Methoxy-O-demethylencainide
  • 3-Methoxy-O-desmethylencainide
  • 4-hydroxy-3-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide
  • Benzamide, 4-hydroxy-3-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)-, (+-)-
  • Bmy 40327
  • Mj 14030
  • Modecainida
  • See more synonyms
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