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CAS 81403-68-1

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Alfuzosin hydrochloride

Description:
Alfuzosin hydrochloride is a medication primarily used to treat benign prostatic hyperplasia (BPH) in men, facilitating urinary flow by relaxing the muscles in the prostate and bladder neck. It belongs to the class of drugs known as alpha-1 adrenergic antagonists. The chemical formula for alfuzosin hydrochloride is C19H23N3O4S·HCl, indicating the presence of a sulfonamide group, which contributes to its pharmacological activity. Alfuzosin is characterized by its relatively high lipophilicity, allowing for effective absorption and distribution in the body. The hydrochloride salt form enhances its solubility in water, facilitating oral administration. Common side effects may include dizziness, fatigue, and hypotension, particularly upon initiation of therapy. Alfuzosin is typically administered once daily, and its pharmacokinetics are influenced by factors such as food intake, which can affect its absorption. Overall, alfuzosin hydrochloride is an important therapeutic agent in managing urinary symptoms associated with prostate enlargement.
Formula:C19H27N5O4·ClH
InChI:InChI=1S/C19H27N5O4.ClH/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19;/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23);1H
InChI key:InChIKey=YTNKWDJILNVLGX-UHFFFAOYSA-N
SMILES:NC=1C2=C(N=C(N(CCCNC(=O)C3CCCO3)C)N1)C=C(OC)C(OC)=C2.Cl
Synonyms:
  • 2-Furancarboxamide
  • 2-Furancarboxamide, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-, hydrochloride
  • 2-Furancarboxamide, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-, hydrochloride (1:1)
  • 2-Furancarboxamide, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-, monohydrochloride
  • Alfoten
  • Alfuzosin Hcl
  • Alfuzosin Hydrochloride
  • Alfuzosina [Spanish]
  • Alfuzosine [French]
  • Alfuzosinehydrochloride
  • See more synonyms
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Found 16 products.