CAS 81409-90-7
:Cabergoline
Description:
Cabergoline is a synthetic ergoline derivative primarily used as a dopamine agonist in the treatment of conditions such as hyperprolactinemia and Parkinson's disease. It functions by selectively stimulating dopamine D2 receptors, which helps to inhibit prolactin secretion from the pituitary gland. The substance is characterized by its high oral bioavailability and long half-life, allowing for once or twice weekly dosing. Cabergoline is typically administered in tablet form and is well-absorbed in the gastrointestinal tract. Its chemical structure includes a bicyclic ring system, which is common among ergoline compounds, contributing to its pharmacological activity. Common side effects may include nausea, dizziness, and fatigue, while more serious effects can involve cardiovascular complications. Due to its potent effects, cabergoline is often monitored closely in clinical settings to ensure patient safety and efficacy of treatment. Overall, cabergoline represents a significant advancement in the management of disorders related to dopamine dysregulation.
Formula:C26H37N5O2
InChI:InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21-,23-/m1/s1
InChI key:InChIKey=KORNTPPJEAJQIU-KJXAQDMKSA-N
SMILES:C(C=C)N1[C@]2([C@@](C=3C=4C(C2)=CNC4C=CC3)(C[C@@H](C(N(C(NCC)=O)CCCN(C)C)=O)C1)[H])[H]
Synonyms:- (8-Beta)-(2-Propenyl)
- (8b)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)- ergoline-8-carboxamide
- (8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide
- (8β,10ξ)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide
- 6-Allyl-N-[3-(Dimethylamino)Propyl]-N-(Ethylcarbamoyl)Ergoline-8-Carboxamide
- Cabaser
- Cabaseril
- Dostine
- Dostinex
- Ergoline-8-carboxamide, N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)-
- Ergoline-8-carboxamide, N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-, (8β)-
- FCE-21336,Cabaser,Dostinex
- Galastop
- N-(3-(Dimethylamino)Propyl)-N-((Ethylamino)Carbonyl)-6-Ergoline-8-Carboxamid
- Sogilen
- Velactis
- See more synonyms
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Found 11 products.
Cabergoline
CAS:Alkaloids of rye ergot and their derivatives; salts thereof, nesoiFormula:C26H37N5O2Color and Shape:PowderMolecular weight:451.6Cabergoline-d6
CAS:Formula:C26H31D6N5O2Color and Shape:White To Off-White SolidMolecular weight:457.65Cabergoline
CAS:<p>Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.</p>Formula:C26H37N5O2Purity:97.69% - 99.86%Color and Shape:White Crystalline SolidMolecular weight:451.6Cabergoline
CAS:Formula:C26H37N5O2Purity:≥ 98.0%Color and Shape:White solid or powderMolecular weight:451.60Cabergoline 1000 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C26H37N5O2Color and Shape:Single SolutionMolecular weight:451.60(8β)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl] -6-(2-propen-1-yl)-ergoline-8-carboxamide
CAS:<p>Agonist of D2 dopamine receptors</p>Formula:C26H37N5O2Purity:Min. 95%Color and Shape:PowderMolecular weight:451.6 g/molCabergoline
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Cabergoline is an ergot derivative and a dopamine D2-receptor agonist (1,2,3). It inhibits the secretion of prolactin and growth hormone.<br>References (1) Kvernmo, T., et al.: Clin.Ther. 28 1065 (2006)(2) Boutinaud, M., et al.: J Dairy Sci. 99, 5707 (2016)(3) Hutton, J.T., et al.: Neurology, 46, 1062 (1996<br></p>Formula:C26H37N5O2Color and Shape:White To Off-WhiteMolecular weight:451.60
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