CAS 81409-90-7: Cabergoline

Description: Cabergoline is a synthetic ergoline derivative primarily used as a dopamine agonist in the treatment of conditions such as hyperprolactinemia and Parkinson's disease. It functions by selectively stimulating dopamine D2 receptors, which helps to inhibit prolactin secretion from the pituitary gland. The substance is characterized by its high oral bioavailability and long half-life, allowing for once or twice weekly dosing. Cabergoline is typically administered in tablet form and is well-absorbed in the gastrointestinal tract. Its chemical structure includes a bicyclic ring system, which is common among ergoline compounds, contributing to its pharmacological activity. Common side effects may include nausea, dizziness, and fatigue, while more serious effects can involve cardiovascular complications. Due to its potent effects, cabergoline is often monitored closely in clinical settings to ensure patient safety and efficacy of treatment. Overall, cabergoline represents a significant advancement in the management of disorders related to dopamine dysregulation.

Formula: C₂₆H₃₇N₅O₂

InChI: InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21-,23-/m1/s1

InChI key: InChIKey=KORNTPPJEAJQIU-KJXAQDMKSA-N

SMILES: O=C(NCC)N(C(=O)C1CN(CC=C)C2CC3=CNC4=CC=CC(=C43)C2C1)CCCN(C)C

Synonyms:

• (8-Beta)-(2-Propenyl)
• (8b)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)- ergoline-8-carboxamide
• (8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide
• (8β,10ξ)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-prop-2-en-1-ylergoline-8-carboxamide
• 6-Allyl-N-[3-(Dimethylamino)Propyl]-N-(Ethylcarbamoyl)Ergoline-8-Carboxamide
• Cabaser
• Cabaseril
• Dostine
• Dostinex
• Ergoline-8-carboxamide, N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-, (8β)-
• Ergoline-8-carboxamide, N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-, (8β)-
• FCE-21336,Cabaser,Dostinex
• Galastop
• N-(3-(Dimethylamino)Propyl)-N-((Ethylamino)Carbonyl)-6-Ergoline-8-Carboxamid
• Sogilen
• Velactis
• Cabergoline

Cabergoline CRS

CAS: 81409-90-7

Cabergoline

CAS: 81409-90-7

Alkaloids of rye ergot and their derivatives; salts thereof, nesoi

• Formula: C₂₆H₃₇N₅O₂
• Color and Shape: Powder
• Molecular weight: 451.29473

Cabergoline

CAS: 81409-90-7

Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.

• Formula: C₂₆H₃₇N₅O₂
• Purity: 99.86%
• Color and Shape: White Crystalline Solid
• Molecular weight: 451.6

Cabergoline-d6

CAS: 81409-90-7

• Formula: C₂₆H₃₁D₆N₅O₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 457.65

Cabergoline

CAS: 81409-90-7

• Formula: C₂₆H₃₇N₅O₂
• Color and Shape: White To Off-White Solid
• Molecular weight: 451.62

Cabergoline

CAS: 81409-90-7

• Purity: 99%
• Molecular weight: 451.6g/mol

Cabergoline

CAS: 81409-90-7

• Formula: C₂₆H₃₇N₅O₂
• Purity: ≥ 98.0%
• Color and Shape: White solid or powder
• Molecular weight: 451.60

Cabergoline 1000 µg/mL in Acetonitrile

CAS: 81409-90-7

• Formula: C₂₆H₃₇N₅O₂
• Color and Shape: Single Solution
• Molecular weight: 451.60

Cabergoline RS

CAS: 81409-90-7

• Color and Shape: White

Cabergoline

CAS: 81409-90-7

Stability Hygroscopic Applications Cabergoline is an ergot derivative and a dopamine D2-receptor agonist (1,2,3). It …

• Formula: C₂₆H₃₇N₅O₂
• Color and Shape: White To Off-White
• Molecular weight: 451.60

(8β)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl] -6-(2-propen-1-yl)-ergoline-8-carboxamide

CAS: 81409-90-7

Agonist of D2 dopamine receptors

• Formula: C₂₆H₃₇N₅O₂
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 451.6 g/mol