CAS 81480-40-2

oleic acid N-hydroxysuccinimide ester

Description:

Oleic acid N-hydroxysuccinimide ester, with the CAS number 81480-40-2, is a chemical compound that combines the fatty acid oleic acid with N-hydroxysuccinimide (NHS), a common reagent in bioconjugation and peptide synthesis. This compound typically exhibits characteristics associated with both its fatty acid and NHS components. Oleic acid is a monounsaturated fatty acid known for its hydrophobic properties, while NHS is a water-soluble, reactive moiety that facilitates the formation of stable amide bonds with amines. The esterification of oleic acid with NHS results in a compound that can be used in various applications, including drug delivery systems, bioconjugation, and as a coupling agent in the synthesis of biomolecules. The presence of the NHS group enhances the reactivity of the oleic acid, allowing for selective conjugation to target molecules. Overall, oleic acid N-hydroxysuccinimide ester is valued for its ability to combine hydrophobic and hydrophilic characteristics, making it useful in biochemical and pharmaceutical contexts.

Formula: C₂₂H₃₇NO₄

InChI: InChI=1S/C22H37NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(26)27-23-20(24)18-19-21(23)25/h9-10H,2-8,11-19H2,1H3/b10-9-

InChI key: MAKGRQMFNNEEKW-KTKRTIGZSA-N

SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)ON1C(=O)CCC1=O

Oleic Acid N-Hydroxysuccinimide

CAS: 81480-40-2

Formula: C₂₂H₃₇NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 379.5335

Ref: IN-DA00G4WM

2,5-Dioxopyrrolidin-1-yl oleate

CAS: 81480-40-2

2,5-Dioxopyrrolidin-1-yl oleate

Formula: C₂₂H₃₇NO₄

Purity: 98%

Molecular weight: 379.54

Ref: 54-OR1060593

Oleic Acid N-Hydroxysuccinimide

CAS: 81480-40-2

Applications Oleic Acid N-Hydroxysuccinimide is an inhibitor of CD36/FAT translocase, and an inhibitor of the mitochondrial respiratory chain. Also it us used in the preparation of ceramide analogues as skin permeation enhancers.
References Drahota, Z. et al.: Biochm. Biophys. Res. Comm., 391, 1348 (2010); Vavrova, K. et al.: Bioorg. Med. Chem., 11, 5381 (2003);

Formula: C₂₂H₃₇NO₄

Color and Shape: Neat

Molecular weight: 379.53

Ref: TR-O524300

2,5-Dioxopyrrolidin-1-yl oleate

CAS: 81480-40-2

2,5-Dioxopyrrolidin-1-yl oleate

Formula: C₂₂H₃₇NO₄

Purity: 98%

Molecular weight: 379.53

Ref: IN-DG01283419

2,5-Dioxopyrrolidin-1-yl oleate

CAS: 81480-40-2

Purity: 98%

Molecular weight: 379.27

Ref: 10-F576346

Oleic Acid N-Hydroxysuccinimide-d17

Controlled Product

CAS: 81480-40-2

Formula: C₂₂D₁₇H₂₀NO₄

Color and Shape: Neat

Molecular weight: 396.638

Ref: TR-O524302

Oleic acid N-hydroxysuccinimide

CAS: 81480-40-2

Oleic acid N-hydroxysuccinimide is a fatty acid that is used as a modulator of cellular uptake, which can be used to treat metabolic disorders and cancer. This compound inhibits carnitine palmitoyltransferase (CPT), which prevents the transport of long-chain fatty acids into the mitochondria. It has been shown to inhibit mitochondrial membrane potential in cells and to cause apoptosis. Oleic acid N-hydroxysuccinimide may also be used for the treatment of autoimmune diseases and HIV infection.

Formula: C₂₂H₃₇NO₄

Purity: Min. 95%

Molecular weight: 379.5 g/mol

Ref: 3D-GDA48040