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CAS 81485-25-8

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Acyclic retinoid

Description:
Acyclic retinoid, identified by its CAS number 81485-25-8, is a synthetic derivative of vitamin A (retinol) that exhibits a range of biological activities, particularly in the context of cancer prevention and treatment. This compound is characterized by its acyclic structure, which differentiates it from traditional cyclic retinoids. Acyclic retinoid is known for its ability to modulate gene expression, influence cell differentiation, and exhibit anti-proliferative effects on various cancer cell lines. It functions primarily through activation of retinoic acid receptors (RARs) and retinoid X receptors (RXRs), which are crucial for regulating cellular processes. Additionally, acyclic retinoid has shown promise in the treatment of liver diseases, particularly in reducing the risk of hepatocellular carcinoma in patients with chronic liver conditions. Its pharmacokinetics and safety profile are subjects of ongoing research, as understanding these aspects is vital for its therapeutic application. Overall, acyclic retinoid represents a significant area of interest in medicinal chemistry and oncology.
Formula:C20H30O2
InChI:InChI=1/C20H30O2/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-19(5)15-20(21)22/h8-9,11,13-15H,6-7,10,12H2,1-5H3,(H,21,22)/b14-8+,17-11+,18-13+,19-15+
InChI key:InChIKey=UUBHZHZSIKRVIV-KCXSXWJSSA-N
SMILES:C(=C(/CC/C=C(/CCC=C(C)C)\C)\C)\C=C\C(=C\C(O)=O)\C
Synonyms:
  • (2E,4E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,4,6,10,14-pentaenoic acid
  • 2,4,6,10,14-Hexadecapentaenoic acid, 3,7,11,15-tetramethyl-, (2E,4E,6E,10E)-
  • 2,4,6,10,14-Hexadecapentaenoic acid, 3,7,11,15-tetramethyl-, (all-E)-
  • 4,5-Didehydrogeranyl geranoic acid
  • 4,5-Didehydrogeranylgeranoic acid
  • Acyclic retinoid
  • E-5166
  • Nik-333
  • Nk-333
  • Peretinoin
  • See more synonyms
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