CAS 81485-25-8

Acyclic retinoid

Description:

Acyclic retinoid, identified by its CAS number 81485-25-8, is a synthetic derivative of vitamin A (retinol) that exhibits a range of biological activities, particularly in the context of cancer prevention and treatment. This compound is characterized by its acyclic structure, which differentiates it from traditional cyclic retinoids. Acyclic retinoid is known for its ability to modulate gene expression, influence cell differentiation, and exhibit anti-proliferative effects on various cancer cell lines. It functions primarily through activation of retinoic acid receptors (RARs) and retinoid X receptors (RXRs), which are crucial for regulating cellular processes. Additionally, acyclic retinoid has shown promise in the treatment of liver diseases, particularly in reducing the risk of hepatocellular carcinoma in patients with chronic liver conditions. Its pharmacokinetics and safety profile are subjects of ongoing research, as understanding these aspects is vital for its therapeutic application. Overall, acyclic retinoid represents a significant area of interest in medicinal chemistry and oncology.

Formula: C₂₀H₃₀O₂

InChI: InChI=1/C20H30O2/c1-16(2)9-6-10-17(3)11-7-12-18(4)13-8-14-19(5)15-20(21)22/h8-9,11,13-15H,6-7,10,12H2,1-5H3,(H,21,22)/b14-8+,17-11+,18-13+,19-15+

InChI key: InChIKey=UUBHZHZSIKRVIV-KCXSXWJSSA-N

SMILES: C(=C(/CC/C=C(/CCC=C(C)C)\C)\C)\C=C\C(=C\C(O)=O)\C

Synonyms:

• (2E,4E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,4,6,10,14-pentaenoic acid
• 2,4,6,10,14-Hexadecapentaenoic acid, 3,7,11,15-tetramethyl-, (2E,4E,6E,10E)-
• 2,4,6,10,14-Hexadecapentaenoic acid, 3,7,11,15-tetramethyl-, (all-E)-
• 4,5-Didehydrogeranyl geranoic acid
• 4,5-Didehydrogeranylgeranoic acid
• Acyclic retinoid
• E-5166
• Nik-333
• Nk-333
• Peretinoin
• Polyprenoic acid
• all-trans-3,7,11,15-Tetramethyl-2,4,6,10,14-hexadecapentaenoic acid
• (2E,4E,6E,10E)-3,7,11,15-Tetramethyl-2,4,6,10,14-hexadecapentaenoic acid
• 4,5-Dehydrogeranylgeranoic acid
• Polyprenic
• POLYPRENOICACID
• 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid
• (2E,4E,6E,10E)-3,7,11,15-tetraMethyl
• hexadeca-2,4,6,10,14-pentaenoic acid
• NIK-333;NIK333;NIK 333

2,​4,​6,​10,​14-​Hexadecapentaenoic acid, 3,​7,​11,​15-​tetramethyl-​, (2E,​4E,​6E,​10E)​-

CAS: 81485-25-8

Formula: C₂₀H₃₀O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 302.4510

Ref: IN-DA008MBR

Peretinoin

CAS: 81485-25-8

Peretinoin

Purity: ≥95%

Molecular weight: 302.45g/mol

Ref: 54-BUP09078

Peretinoin

CAS: 81485-25-8

Formula: C₂₀H₃₀O₂

Purity: ≥ 90%

Color and Shape: Off-white to beige or brown solid

Molecular weight: 302.45

Ref: 7W-GX4932

Peretinoin

CAS: 81485-25-8

Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.

Formula: C₂₀H₃₀O₂

Purity: 97.23%

Color and Shape: Solid

Molecular weight: 302.45

Ref: TM-TQ0064

(2E,4E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,4,6,10,14-pentaenoic acid

CAS: 81485-25-8

Purity: 95.0%

Molecular weight: 302.4580078125

Ref: 10-F462890

Peretinoin

Controlled Product

CAS: 81485-25-8

Formula: C₂₀H₃₀O₂

Color and Shape: Neat

Molecular weight: 302.45

Ref: TR-P286120