CAS 81486-22-8

Nipradilol

Description:

Nipradilol is a pharmaceutical compound primarily used as an antihypertensive agent. It belongs to the class of beta-blockers and exhibits both beta-adrenergic blocking and alpha-1 adrenergic blocking properties, which contribute to its effectiveness in lowering blood pressure. The chemical structure of nipradilol includes a phenolic hydroxyl group, which is significant for its pharmacological activity. It is typically administered orally and is known for its ability to improve blood flow and reduce heart rate. Additionally, nipradilol has been studied for its potential benefits in treating conditions such as glaucoma due to its ability to lower intraocular pressure. The compound is characterized by its moderate solubility in water and is often formulated in various dosage forms for clinical use. As with many medications, it is essential to consider potential side effects and contraindications, which may include dizziness, fatigue, or respiratory issues, particularly in patients with pre-existing conditions. Overall, nipradilol represents a valuable option in the management of hypertension and related cardiovascular conditions.

Formula: C₁₅H₂₂N₂O₆

InChI: InChI=1/C15H22N2O6/c1-10(2)16-7-12(18)8-21-14-5-3-4-11-6-13(23-17(19)20)9-22-15(11)14/h3-5,10,12-13,16,18H,6-9H2,1-2H3

InChI key: InChIKey=OMCPLEZZPVJJIS-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)C)O)C1=C2C(CC(ON(=O)=O)CO2)=CC=C1

Synonyms:

• 2H-1-Benzopyran-3-ol, 3,4-dihydro-8-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, 3-nitrate
• 3,4-Dihydro-8-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2H-1-benzopyran-3-ol 3-nitrate
• 3,4-Dihydro-8-(2-hydroxy-3-(isopropylamino)propoxy)-2H-1-benzopyran-3-ol 3-nitrate
• 3,4-Dihydro-8-(2-hydroxy-3-isopropylamino)propoxy-3-nitroxy-2H-1-benzopyran
• 8-(2-Hydroxy-3-(isopropylamino)propoxy)-3-chromanol 3-nitrate
• 8-(2-Hydroxy-3-(isopropylamino)propoxy)-3-chromanyl nitrat
• 8-[2-hydroxy-3-(propan-2-ylamino)propoxy]-3,4-dihydro-2H-chromen-3-yl nitrate
• Brn 3566879
• Ccris 2515
• Hypadil
• K 351
• Kt 210
• Nipradilol [INN:JAN]
• Nipradilolum
• Nipradilolum [Latin]
• Nipradolol
• Unii-Fvm336I71Y
• Nipradilol
• Nipranol
• NIPRANOL;NIPRADOLOL;NIPRADILOL;BRN 3566879
• 8-(2-Hydroxy-3-(isopropylaMino)propoxy)chroMan-3-yl nitrate

Nipradilol

CAS: 81486-22-8

Formula: C₁₅H₂₂N₂O₆

Molecular weight: 326.35

Ref: 7W-GP3202

Nipradolol

Controlled Product

CAS: 81486-22-8

Formula: C₁₅H₂₂N₂O₆

Color and Shape: Neat

Molecular weight: 326.345

Ref: TR-N478950

Nipradolol-d7

Controlled Product

CAS: 81486-22-8

Formula: C₁₆D₇H₁₇N₂O₅

Color and Shape: Neat

Molecular weight: 331.415

Ref: TR-N478952

Nipradolol

CAS: 81486-22-8

Nipradolol is a selective β-adrenergic receptor antagonist. It is used to treat bowel diseases, including constipation and diarrhea. Nipradolol has been shown to inhibit the release of cytosolic Ca2+ in intestinal cells by inhibiting the activity of sodium-dependent glucose co-transporter 1 (SGLT1). Nipradolol has also been shown to have antimicrobial activity against bacteria such as Escherichia coli, Salmonella enterica, and Staphylococcus aureus. This drug may be used for the treatment of inflammatory bowel disease (IBD) or other intestinal disorders induced by ischemia reperfusion. Nipradolol can also be used for cardiac prophylaxis in high-risk patients undergoing noncardiac surgery. The drug inhibits cardiac ion channels and blocks the action of catecholamines on these channels. This agent has also been found to be useful for fetal bov

Formula: C₁₅H₂₂N₂O₆

Purity: Min. 95%

Molecular weight: 326.34 g/mol

Ref: 3D-GDA48622

Nipradolol

CAS: 81486-22-8

Nipradolol blocks alpha-1-adrenergic receptors, lowers IOP in rabbits, and reduces NA-induced muscle contraction and dog artery vasodilation.

Formula: C₁₅H₂₂N₂O₆

Color and Shape: Solid

Molecular weight: 326.35

Ref: TM-T73083