CAS 81490-05-3

2-{[(2,3-dihydroxypropoxy)(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate

Description:

The chemical substance known as "2-{[(2,3-dihydroxypropoxy)(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate" with CAS number 81490-05-3 is a complex phospholipid derivative. It features a glycerol backbone modified with various functional groups, including a phosphoryl group and fatty acid chains, which contribute to its amphiphilic nature. This amphiphilicity allows the molecule to interact with both hydrophilic and hydrophobic environments, making it suitable for applications in drug delivery and membrane biology. The presence of multiple hydroxyl groups enhances its solubility in aqueous solutions and may facilitate interactions with biological membranes. Additionally, the long-chain fatty acid moieties provide structural stability and influence the molecule's behavior in lipid bilayers. Its specific configuration, including the (9Z)-octadec-9-enoate moiety, indicates the presence of a cis double bond, which can affect the fluidity and permeability of membranes. Overall, this compound's unique structural features make it a subject of interest in biochemical and pharmaceutical research.

Formula: C₄₀H₇₇O₁₀P

InChI: InChI=1/C40H77O10P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-40(44)50-38(36-49-51(45,46)48-34-37(42)33-41)35-47-39(43)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37-38,41-42H,3-16,19-36H2,1-2H3,(H,45,46)/b18-17-

SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCCC)COP(=O)(O)OCC(CO)O

Synonyms:

• 1-Hexadecanoyl-2-[Cis-9-Octadecanoyl]-Sn-Glycero-3-[Phospho-Rac-(1-Glycerol)] Ammonium Salt

Palmitoyloleoylphosphatidylglycerol

CAS: 81490-05-3

Palmitoyloleoylphosphatidylglycerol is an anionic surfactant lipid that is effective in inhibiting the inflammatory response of lung epithelial cells and macrophages induced by Der p2 stimulation.

Formula: C₄₀H₇₇O₁₀P

Color and Shape: Solid

Molecular weight: 749.01

Ref: TM-TCL-00078