CAS 81586-97-2

Estra-1,3,5(10)-trien-17-one-1,4,16,16-d4,2,3-dihydroxy-

Description:

Estra-1,3,5(10)-trien-17-one-1,4,16,16-d4,2,3-dihydroxy- is a synthetic derivative of estradiol, a naturally occurring estrogen. This compound is characterized by its specific molecular structure, which includes a steroid backbone with a triene configuration and hydroxyl groups at the 2 and 3 positions, contributing to its biological activity. The presence of deuterium (d4) indicates that certain hydrogen atoms in the molecule have been replaced with deuterium isotopes, which can be useful in studies involving metabolic pathways or pharmacokinetics. This compound is primarily used in research settings, particularly in studies related to hormonal activity, receptor binding, and the effects of estrogenic compounds on biological systems. Its unique structural features allow for the exploration of its interactions with estrogen receptors and its potential therapeutic applications in hormone-related conditions. As with many steroid derivatives, it is important to handle this substance with care, adhering to safety protocols due to its biological activity.

Formula: C₁₈H₁₈D₄O₃

Synonyms:

• 2-Hydroxyestrone-1,4,16,16-D4

2-Hydroxyestrone-1,4,16,16-d4

CAS: 81586-97-2

Purity: 98 atom % D

Color and Shape: White-Yellow Solid

Molecular weight: 290.39

Ref: 3U-D5806

2-Hydroxy Estrone-d4

Controlled Product

CAS: 81586-97-2

Applications A labelled metabolite of Estradiol (E888000).
References Fishman, H.G, et al.: Biochemistry, 8, 4304 (1969), Ryan, Sugar, J., et al.: J. Clin. Endocrinol. Metab., 50, 137 (1980), Numazawa, M., et al.: Steroids, 38, 149 (1981), Travis, R., et al.: Breast Cancer Res., 5, 239 (2003),

Formula: C₁₈₂H₄H₁₈O₃

Color and Shape: Grey

Molecular weight: 290.39

Ref: TR-H941947