CAS 816-66-0

4-Methyl-2-oxovaleric acid

Description:

4-Methyl-2-oxovaleric acid, also known as 4-methyl-2-oxopentanoic acid, is an organic compound characterized by its carboxylic acid functional group and a ketone group. It features a five-carbon chain with a methyl group at the fourth position and a keto group at the second position, contributing to its unique reactivity and properties. This compound is typically a colorless to pale yellow liquid or solid, depending on its state at room temperature. It is soluble in polar solvents, such as water and alcohols, due to the presence of the carboxylic acid group. 4-Methyl-2-oxovaleric acid is of interest in various fields, including biochemistry and pharmaceuticals, as it can serve as an intermediate in the synthesis of other compounds. Its reactivity allows it to participate in various chemical reactions, including esterification and condensation. Safety data indicates that, like many organic acids, it should be handled with care to avoid irritation to skin and mucous membranes.

Formula: C₆H₁₀O₃

InChI: InChI=1/C6H10O3/c1-5(6(8)9)3-2-4-7/h4-5H,2-3H2,1H3,(H,8,9)

InChI key: InChIKey=BKAJNAXTPSGJCU-UHFFFAOYSA-N

SMILES: C(CC(C)C)(C(O)=O)=O

Synonyms:

• 2-Ketoisocaproic acid
• 2-Oxo-4-methylpentanoic acid
• 2-Oxo-4-methylvaleric acid
• 2-Oxoisocaproic acid
• 2-Oxoleucine
• 2-keto-4-Methylvaleric acid
• 4-Methyl-2-Oxovaleric Acid
• 4-Methyl-2-oxopentanoate
• 4-Methyl-2-oxopentanoic acid
• 4-Methyl-2-oxovaleriansaure
• Acide 4-methyl-2-oxovalerique
• Acido 4-Metil-2-Oxovalerico
• Isobutylglyoxylic acid
• Ketoisocaproic acid
• Ketoleucine
• Valeric Acid, 4-Methyl-2-Oxo-
• α-Ketoisocaproic acid
• α-Ketoisocapronic acid
• α-Oxoisocaproic acid
• 2-KETO-ISO-HEXANOIC ACID
• 4-methyl-2-oxo-pentanoicaci
• Isopropylpyruvicacid
• 2-methyl-5-oxopentanoic acid
• 2-KETO-4-METHYL-N-PENTANOIC ACID
• 2-keto-isocaproate
• Pentanoic acid, 4-methyl-2-oxo-
• ALPHA-KETOISOCAPROIC ACID
• 2-KETO-ISO-CAPROIC ACID
• 2-KETO-4-METHYLPENTANOIC ACID
• Pentanoic acid, 4-methyl-2-oxo-
• 2-Oxoisocaproic acid, 4-Methyl-2-oxopentanoic acid, Ketoleucine
• 4-METHYL-2-OXOVALERIC ACID 95+%

4-Methyl-2-oxovaleric Acid

CAS: 816-66-0

Formula: C₆H₁₀O₃

Purity: >95.0%(GC)(T)

Color and Shape: Colorless to Yellow clear liquid

Molecular weight: 130.14

Ref: 3B-K0025

4-Methyl-2-oxovaleric acid, 94%

CAS: 816-66-0

Ii is an intermediate in the metabolism of leucine and also used as flavoring agents. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / ite

Formula: C₆H₉NaO₃

Purity: 94%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 152.13

Ref: 02-H60076

4-Methyl-2-oxopentanoic acid

CAS: 816-66-0

Formula: C₆H₁₀O₃

Purity: 90%

Color and Shape: Liquid

Molecular weight: 130.1418

Ref: IN-DA003LQB

4-Methyl-2-Oxovaleric Acid

CAS: 816-66-0

4-Methyl-2-Oxovaleric Acid

Purity: 98%

Molecular weight: 130.14g/mol

Ref: 54-OR1011608

4-Methyl-2-oxopentanoic acid

CAS: 816-66-0

4-Methyl-2-oxopentanoic acid

Purity: ≥98%

Molecular weight: 130.14g/mol

Ref: 54-BUP16590

4-Methyl-2-oxopentanoic acid

CAS: 816-66-0

4-Methyl-2-oxopentanoic acid, an abnormal metabolite and neurotoxin, results from improper branched-chain amino acid metabolism.

Formula: C₆H₁₀O₃

Purity: 99.09%

Color and Shape: Liquid

Molecular weight: 130.14

Ref: TM-T5071

4-Methyl-2-oxovaleric Acid

Controlled Product

CAS: 816-66-0

Formula: C₆H₁₀O₃

Color and Shape: Neat

Molecular weight: 130.14

Ref: TR-M220748

Calcium 2-Keto-4-methylvalerate Hydrate

Controlled Product

CAS: 816-66-0

Stability Hygroscopic
Applications Calcium 2-keto-4-methylvalerate ketoacid that can be used as a phosphate binder alternative for patients on peritoneal dialysis, and can be used as a supplement for very low protein diets to maintain nutritional status of patients of chronic kidney disease until arteriovenous fistula made or training for peritoneal dialysis given.
References Macia, M., et al.: Clin. Nephrol., 48, 181 (1997); Duenhas, M., et al.: Clin. Nephrol., 79, 387 (2013);

Formula: (C₆H₉O₃)₂•Ca•x(H₂O)

Color and Shape: Off-White

Molecular weight: 2(129.13) + 40.08 + x(18.02)

Ref: TR-C145777

α-Ketoisocaproicacid

CAS: 816-66-0

α-Ketoisocaproicacid is an intermediate in the biosynthesis of leucine from α-ketoglutarate. This compound is formed by the decarboxylation of α-ketoglutarate and has been shown to inhibit voltage-dependent calcium channels. It also has a role in regulating intracellular Ca2+ levels, which may be due to its ability to cause cell death in wild type cells. α-Ketoisocaproicacid is an intermediate in the biosynthesis of leucine from α-ketoglutarate. This compound is formed by the decarboxylation of α-ketoglutarate and has been shown to inhibit voltage-dependent calcium channels. It also has a role in regulating intracellular Ca2+ levels, which may be due to its ability to cause cell death in wild type cells. The reaction mechanism involves oxidation of α-ketoisocaproic acid by NADH and reduction

Formula: C₆H₁₀O₃

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 130.14 g/mol

Ref: 3D-FK152625

4-Methyl-2-oxopentanoic acid

CAS: 816-66-0

Formula: C₆H₁₀O₃

Purity: 98%

Color and Shape: Liquid, Clear

Molecular weight: 130.143

Ref: 10-F240505