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CAS 816-94-4

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1,2-Distearoyl-sn-glycero-3-phosphocholine

Description:
1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC) is a phospholipid commonly used in biochemistry and pharmaceutical applications. It is characterized by its two long-chain saturated fatty acid tails, specifically stearic acid, which contribute to its hydrophobic properties, and a phosphocholine head group that imparts hydrophilicity. This amphiphilic nature allows DSPC to form lipid bilayers, making it a crucial component in the formation of liposomes and lipid nanoparticles for drug delivery systems. DSPC has a high phase transition temperature, which enhances the stability of lipid formulations at physiological temperatures. It is also known for its ability to encapsulate hydrophilic and hydrophobic compounds, making it versatile in various applications, including vaccine delivery and gene therapy. Additionally, DSPC is biocompatible and biodegradable, which is essential for its use in medical and cosmetic formulations. Its structural integrity and functionality make it a valuable substance in the development of nanocarriers and other lipid-based systems in research and clinical settings.
Formula:C44H88NO8P
InChI:InChI=1/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1
InChI key:InChIKey=NRJAVPSFFCBXDT-HUESYALOSA-N
SMILES:[C@H](OC(CCCCCCCCCCCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCCCC)=O
Synonyms:
  • (2R)-2,3-bis(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
  • (R)-(7-Lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium 4-oxide
  • (R)-(7-Lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium-4-oxid
  • 1,2-<span class="text-smallcaps">L</span>-α-Distearoylphosphatidylcholine
  • 1,2-Bis(stearoyl)-sn-glycero-3-phosphocholine
  • 1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine
  • 1,2-Distearoyl-3-sn-phosphatidylcholine
  • 1,2-Distearoyl-<span class="text-smallcaps">L</span>-α-glycerophosphocholine
  • 1,2-Distearoyl-L-α-glycerophosphocholine
  • 1,2-Distearoyl-sn-3-phosphacholine
  • See more synonyms
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Purity (%)
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100
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0
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50
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90
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95
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100
Found 16 products.