CAS 81627-83-0

Macrophage colony-stimulating factor

Description:

Macrophage colony-stimulating factor (M-CSF), also known as CSF-1, is a glycoprotein that plays a crucial role in the regulation of hematopoiesis and the immune response. It is primarily involved in the differentiation and proliferation of monocytes and macrophages, promoting their survival and activation. M-CSF is produced by various cell types, including fibroblasts, endothelial cells, and certain immune cells, in response to inflammatory stimuli. The protein functions by binding to its receptor, CSF-1R, which triggers signaling pathways that enhance macrophage function and promote tissue repair. M-CSF is also implicated in various physiological and pathological processes, including wound healing, bone metabolism, and cancer progression. Its therapeutic potential is being explored in various contexts, including immunotherapy and regenerative medicine. The CAS number 81627-83-0 identifies the specific molecular structure of M-CSF, which is essential for research and clinical applications. Overall, M-CSF is a vital cytokine with significant implications for immune system regulation and cellular communication.

Formula: Unspecified

Synonyms:

• Colony-stimulating factor 1
• Macrophage-monocyte colony-stimulating factor
• Cytokines, macrophage colony-stimulating factor
• Macrophage colony-stimulating factor
• Lymphokines, macrophage colony-stimulating factor