CAS 81691-06-7

3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione

Description:

3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione, also known by its CAS number 81691-06-7, is a nucleoside analog characterized by its pyrimidine structure, which includes a ribofuranosyl sugar moiety. This compound features a methyl group at the 3-position of the pyrimidine ring and is known for its potential biological activity, particularly in the context of antiviral and anticancer research. The presence of the ribofuranosyl group suggests that it may interact with nucleic acids, potentially influencing processes such as DNA or RNA synthesis. Its structural characteristics contribute to its solubility and stability, which are important for its biological efficacy. Additionally, the compound may exhibit specific interactions with enzymes or receptors due to its unique functional groups, making it a subject of interest in medicinal chemistry. Overall, 3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione represents a significant area of study for its potential therapeutic applications.

Formula: C₁₀H₁₄N₂O₆

InChI: InChI=1S/C10H14N2O6/c1-12-9(16)4(2-11-10(12)17)8-7(15)6(14)5(3-13)18-8/h2,5-8,13-15H,3H2,1H3,(H,11,17)/t5-,6-,7-,8+/m1/s1

InChI key: InChIKey=DXEJZRDJXRVUPN-XUTVFYLZSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)C=2C(=O)N(C)C(=O)NC2

Synonyms:

• 3-Methylpseudouridine
• 3-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione
• 2,4(1H,3H)-Pyrimidinedione, 3-methyl-5-β-D-ribofuranosyl-
• NSC 363818

3-Methylpsedouridine

CAS: 81691-06-7

Nucleoside Derivatives - C-nucleosides, N-Methyl nucleosides; Naturally modified Ribo-nucleosides

Formula: C₁₀H₁₄N₂O₆

Color and Shape: Solid

Molecular weight: 258.23

Ref: TM-TNU0038

3-Methylpseudouridine

CAS: 81691-06-7

3-Methylpseudouridine is a uridine analog that inhibits the enzyme RNA polymerase. It has been shown to inhibit protein synthesis and can be used in the treatment of bacterial infections. 3-Methylpseudouridine is synthesized by solid-phase chemistry on a polymeric support and purified by high-performance liquid chromatography. It has been shown to inhibit the growth of bacteria in cell culture, but its effects on human cells are not known. 3-Methylpseudouridine also binds with high affinity to calf thymus DNA and it can be used as a substrate for aminoglycoside modification studies.

Formula: C₁₀H₁₄N₂O₆

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 258.23 g/mol

Ref: 3D-NM159403

3-Methylpseudouridine

Controlled Product

CAS: 81691-06-7

Formula: C₁₀H₁₄N₂O₆

Color and Shape: Neat

Molecular weight: 258.228

Ref: TR-M211310