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CAS 81921-35-9

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N6-methyladenosine 5'-monophosphate*sodium

Description:
N6-methyladenosine 5'-monophosphate sodium, commonly referred to as m6A-AMP, is a nucleotide derivative characterized by the presence of a methyl group at the nitrogen-6 position of the adenine base. This modification plays a crucial role in various biological processes, particularly in RNA metabolism and regulation. The compound consists of an adenine base linked to a ribose sugar, which is further connected to a phosphate group at the 5' position. The sodium salt form indicates that the compound is neutralized with sodium ions, enhancing its solubility in aqueous solutions. N6-methyladenosine is known for its involvement in epitranscriptomics, influencing mRNA stability, splicing, and translation. It is also implicated in cellular signaling pathways and gene expression regulation. The compound is often utilized in biochemical research to study RNA modifications and their effects on cellular functions. Its stability and reactivity make it a valuable tool in molecular biology and biochemistry.
Formula:C11H16N5NaO7P
InChI:InChI=1/C11H16N5O7P.Na/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(18)7(17)5(23-11)2-22-24(19,20)21;/h3-5,7-8,11,17-18H,2H2,1H3,(H,12,13,14)(H2,19,20,21);
SMILES:CNc1c2c(ncn1)n(cn2)C1C(C(C(COP(=O)(O)O)O1)O)O.[Na]
Synonyms:
  • 9H-purin-6-amine, N-methyl-9-(5-O-phosphonopentofuranosyl)-, monosodium salt
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