CAS 82-76-8

8-Anilino-1-naphthalenesulfonic acid

Description:

8-Anilino-1-naphthalenesulfonic acid, commonly referred to as ANS, is an organic compound characterized by its sulfonic acid functional group attached to a naphthalene ring, which is further substituted with an aniline group. This compound is typically a yellow to orange solid that is soluble in water, making it useful in various biochemical applications. ANS is known for its role as a fluorescent probe, particularly in studies involving protein folding and conformational changes, as it exhibits significant fluorescence enhancement upon binding to hydrophobic regions of proteins. The sulfonic acid group contributes to its water solubility and ionic character, while the naphthalene moiety provides hydrophobic properties. ANS is also utilized in dyeing processes and as a pH indicator due to its sensitivity to changes in the environment. Its chemical structure allows it to interact with various biomolecules, making it a valuable tool in biochemistry and molecular biology research. Safety precautions should be taken when handling this compound, as it may cause irritation upon contact with skin or eyes.

Formula: C₁₆H₁₃NO₃S

InChI: InChI=1S/C16H13NO3S/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13/h1-11,17H,(H,18,19,20)

InChI key: InChIKey=FWEOQOXTVHGIFQ-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)C=1C=2C(NC3=CC=CC=C3)=CC=CC2C=CC1

Synonyms:

• 1-(Phenylamino)-8-naphthalenesulfonic acid
• 1-Anilino-8-naphthalenesulfonic acid
• 1-Naphthalenesulfonic acid, 8-(phenylamino)-
• 1-Naphthalenesulfonic acid, 8-anilino-
• 1-Phenylaminonaphthalene-8-sulfonic acid
• 8-(Phenylamino)-1-naphthalenesulfonic acid
• 8-(Phenylamino)Naphthalene-1-Sulfonate
• 8-(Phenylamino)Naphthalene-1-Sulfonic Acid
• 8-Anilino-1-naphthalenesulfonate
• 8-Anilino-1-naphthalenesulfonic acid
• 8-Anilinonaphthalene-1-Sulphonic Acid
• 8-Anilinonaphthalin-1-sulfonsaure
• ANS
• ANS (fluorescent probe)
• Acide 8-anilinonaphtalene-1-sulfonique
• Acido 8-Anilinonaftaleno-1-Sulfonico
• Ansa
• Nsc 1746
• Peri acid, phenyl-
• Phenyl peri acid

8-Anilino-1-naphthalenesulfonic Acid

CAS: 82-76-8

Formula: C₁₆H₁₃NO₃S

Purity: >95.0%(T)(HPLC)

Color and Shape: Light gray to Brown to Black powder to crystal

Molecular weight: 299.34

Ref: 3B-A0472

8-Anilinonaphthalene-1-sulfonic acid, 95%

CAS: 82-76-8

Fluorescent probe for proteins on polyacrylamide gels

Formula: C₁₆H₁₃NO₃S

Purity: 95%

Color and Shape: Pale grey to black or brown, Crystals or powder or crystalline powder

Molecular weight: 299.34

Ref: 02-J65332

8-Anilino-1-naphthalenesulfonic acid

CAS: 82-76-8

Formula: C₁₆H₁₃NO₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 299.3443

Ref: IN-DA0034EM

8-Anilino-1-naphthalenesulfonic acid

CAS: 82-76-8

8-Anilino-1-naphthalenesulfonic acid

Formula: C₁₆H₁₃NO₃S

Purity: 95%

Color and Shape: black crystalline solid

Molecular weight: 299.34g/mol

Ref: 54-OR323280

8-Anilino-1-naphthalenesulfonic acid

CAS: 82-76-8

Formula: C₁₆H₁₃NO₃S

Purity: ≥ 95.0%

Color and Shape: Grey to dark green, brown or black powder

Molecular weight: 299.34

Ref: 7W-GT2378

8-Anilino-1-naphthalenesulfonic Acid

Controlled Product

CAS: 82-76-8

Applications 8-Anilino-1-naphthalenesulfonic Acid is used as a fluorescent probe to identify hydrophobic sites. Dyes and metabolites.
References Gonzalez, W.G., Miksovska, J.: BBA Protein Proteomics, 1844, 1472 (2014); Patil, R., et. al.: ACS Chem. Biol., Ahead of Print (2014)

Formula: C₁₆H₁₃NO₃S

Color and Shape: Grey To Black

Molecular weight: 299.34

Ref: TR-A663790

8-(Phenylamino)naphthalene-1-sulfonic acid

CAS: 82-76-8

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 299.3399963378906

Ref: 10-F242645

8-Anilino-1-naphthalenesulfonic acid

CAS: 82-76-8

8-Anilino-1-naphthalenesulfonic acid is a potent and selective inhibitor of the proteasome. It inhibits the activity of the proteasome and leads to neuronal death. 8-Anilino-1-naphthalenesulfonic acid has been shown to have antioxidative properties in a Langmuir adsorption isotherm study. This compound also has fluorescence, which makes it useful as a fluorescent probe for protein identification in human serum. 8-Anilino-1-naphthalenesulfonic acid binds to proteins with hydrophobic regions, such as lipids and phospholipids, due to its hydrophobic effect. It can be used as an analytical method for determining the protein content in water samples.

Formula: C₁₆H₁₃NO₃S

Purity: Min. 95 Area-%

Color and Shape: Brown Green Powder

Molecular weight: 299.35 g/mol

Ref: 3D-FA46083

8-Anilino-1-Naphthalenesulphonic Acid (ANS) extrapure, 98%

CAS: 82-76-8

Formula: C₁₆H₁₃NO₃S

Purity: min. 98%

Color and Shape: Dark green to dark brown to black, Powder, Clear

Molecular weight: 299.34

Ref: SR-42275

8-Anilino-1-naphthalenesulfonic acid

CAS: 82-76-8

8-Anilino-1-naphthalenesulfonic acid (1-Anilinonaphthalene-8-Sulfonic Acid) is a fluorescent probe used for detecting conformational changes in proteins.

Formula: C₁₆H₁₃NO₃S

Purity: 97.09%

Color and Shape: Solid

Molecular weight: 299.34

Ref: TM-T84875