CAS 82-92-8

Cyclizine

Description:

Cyclizine is an antihistamine belonging to the piperazine class, primarily used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness. It is characterized by its ability to cross the blood-brain barrier, which contributes to its effectiveness in alleviating symptoms related to vestibular disturbances. Cyclizine exhibits anticholinergic properties, leading to side effects such as dry mouth, drowsiness, and blurred vision. The substance is typically administered orally and is available in various formulations, including tablets and injectable forms. Its mechanism of action involves blocking histamine H1 receptors, thereby reducing the effects of histamine in the body, which is responsible for allergic reactions and motion sickness. Cyclizine is generally well-tolerated, but caution is advised in patients with certain medical conditions, such as glaucoma or prostate enlargement, due to its anticholinergic effects. Overall, cyclizine is a valuable medication in the management of motion-related ailments, with a well-established safety profile when used as directed.

Formula: C₁₈H₂₂N₂

InChI: InChI=1S/C18H22N2/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18H,12-15H2,1H3

InChI key: InChIKey=UVKZSORBKUEBAZ-UHFFFAOYSA-N

SMILES: C(N1CCN(C)CC1)(C2=CC=CC=C2)C3=CC=CC=C3

Synonyms:

• ( -)-1-Diphenylmethyl-4-methylpiperazine
• (N-Benzhydryl)(N'-methyl)diethylenediamine
• 1-Benzhydryl-4-methylpiperazin
• 1-Methyl-4-(α,α'-diphenylmethyl) piperazine
• Brn 0230441
• Bw 47-83
• Ciclizina
• Ciclizina [INN-Spanish]
• Compound 47-83
• Cyclizin
• Cyclizine [INN:BAN:DCF]
• Cyclizinum
• Cyclizinum [INN-Latin]
• Hsdb 3309
• Marezine
• N-Benzhydryl-N'-methylpiperazine
• N-Methyl-N'-benzhydrylpiperazine
• Nautazine
• Ne-Devomit
• Neo-devomit
• Nsc 26608
• Piperazine, 1-(diphenylmethyl)-4-methyl-
• Unii-Qrw9Fcr9P2
• Wellcome preparation 47-83
• Wellcome prepn 47-83
• 5-23-01-00232 (Beilstein Handbook Reference)

CYCLIZINE HCL

CAS: 82-92-8

Formula: C₁₈H₂₂N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 266.3807

Ref: IN-DA00G25W

Cyclizine

CAS: 82-92-8

Formula: C₁₈H₂₂N₂

Color and Shape: White To Off-White Solid

Molecular weight: 266.39

Ref: 4Z-C-287001

Cyclizine-d4

CAS: 82-92-8

Formula: CC₁₇H₁₉D₃N₂

Molecular weight: 270.40

Ref: 4Z-C-287002

Cyclizine-d4 Lactate

Controlled Product

CAS: 5897-19-8, 82-92-8

Formula: C₂₁H₂₄D₄N₂O₃

Color and Shape: Neat

Molecular weight: 357.459

Ref: TR-C987442

Cyclizine

CAS: 82-92-8

Formula: C₁₈H₂₂N₂

Molecular weight: 266.39

Ref: ST-EA-CP-C146000