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CAS 82-93-9

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(±)-Chlorcyclizine

Description:
(±)-Chlorcyclizine is a chemical compound classified as an antihistamine, primarily used for its antiemetic and antiallergic properties. It belongs to the diphenylmethane class of compounds and is characterized by its ability to block histamine H1 receptors, which helps alleviate symptoms associated with allergies and motion sickness. The compound has a chiral center, resulting in two enantiomers, but the "(±)" designation indicates that it is a racemic mixture of both enantiomers. (±)-Chlorcyclizine is typically administered in oral form and is known for its sedative effects, which can be beneficial in treating conditions like nausea and vomiting. Its chemical structure includes a chlorinated phenyl group, contributing to its pharmacological activity. The substance is generally well-tolerated, although it may cause side effects such as drowsiness, dry mouth, or dizziness. As with any medication, it is important to use (±)-Chlorcyclizine under medical supervision to ensure safety and efficacy.
Formula:C18H21ClN2
InChI:InChI=1S/C18H21ClN2/c1-20-11-13-21(14-12-20)18(15-5-3-2-4-6-15)16-7-9-17(19)10-8-16/h2-10,18H,11-14H2,1H3
InChI key:InChIKey=WFNAKBGANONZEQ-UHFFFAOYSA-N
SMILES:C(C1=CC=C(Cl)C=C1)(N2CCN(C)CC2)C3=CC=CC=C3
Synonyms:
  • Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-methyl-
  • Piperazine, 1-(p-chloro-α-phenylbenzyl)-4-methyl-
  • Chlorcyclizine
  • Chlorcycline
  • 1-[(4-Chlorophenyl)phenylmethyl]-4-methylpiperazine
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