CAS 82128-76-5

Benzeneacetonitrile, 2-fluoro-a-[(trimethylsilyl)oxy]-

Description:

Benzeneacetonitrile, 2-fluoro-a-[(trimethylsilyl)oxy]- is an organic compound characterized by its unique functional groups and structural features. It contains a benzene ring, which contributes to its aromatic properties, and an acetonitrile group that introduces a nitrile functional group, known for its polar characteristics and ability to participate in various chemical reactions. The presence of a fluorine atom at the 2-position of the benzene ring enhances its reactivity and can influence its electronic properties. Additionally, the trimethylsilyl ether group provides stability and solubility in organic solvents, making it useful in synthetic chemistry. This compound is typically utilized in organic synthesis and may serve as an intermediate in the production of pharmaceuticals or agrochemicals. Its properties, such as boiling point, melting point, and solubility, can vary based on the specific conditions and purity of the substance. As with many organic compounds, safety precautions should be observed when handling it due to potential toxicity and reactivity.

Formula: C₁₁H₁₄FNOSi

2-Fluoro-a-[(trimethylsilyl)oxy]benzeneacetonitrile

Controlled Product

CAS: 82128-76-5

Applications 2-Fluoro-α-[(trimethylsilyl)oxy]benzeneacetonitrile is an intermediate in synthesizing 1-Cyclopropyl-2-(2-fluorophenyl)-2-hydroxy-ethanone (C989465), a useful synthetic intermediate in the synthesis of Prasugrel (P701150, HCl); an antiplatelet agent.
References Wiviott, S.D., et al.: Circulation, 116, 2923 (2007); Xu, X., et al. Faming Zhuanli Shenqing. CN 102718642 A 20121010. Oct 10, 2012; Wang, G., et al. Faming Zhuanli Shenqing. CN 101402556 A 20090408. Apr 8, 2009

Formula: C₁₁H₁₄FNOSi

Color and Shape: Neat

Molecular weight: 223.32

Ref: TR-F599038